Sérfræðingur í þróunardeild líftæknilyfja - Frumuræktun / Scientist, USP Development

<p>Alvotech leitar að einstaklingi til að vinna með öflugu lífvísindateymi sem sérhæfir sig í þróun frumuræktunar ferla til framleiðslu á líftæknilyfjahliðstæðum. Alvotech er fjölþjóðlegt fyrirtæki sem starfar með það markmið að auka aðgengi sjúklinga um allan heim að hágæða líftæknilyfjum til meðhöndlunar á erfiðum sjúkdómum eins og gigt, sóríasis og krabbameini.</p><p></p><p><b>Helstu verkefni:</b></p><ul><li><p>Vinna á rannsóknarstofu og meðhöndlun á ýmsum tækjum og búnaði sem tengjast ræktun á erfðabreyttum frumum og framleiðslu á einstofna mótefnum, þar á meðal ræktunartönkum í mismunandi stærðum.</p></li><li><p>Tilraunir, gagnasöfnun, mat, greining og skýrslugerðir með megin markmið að þróa skilvirkan frumuræktunar feril fyrir framleiðslu á líftæknilyfjum.</p></li></ul><p></p><p><b>Menntunar- og hæfniskröfur:</b></p><ul><li><p>Háskólagráða; BSc eða MSc (æskilegt) innan líftækni, iðnaðarlíftækni, lífefnafræði, lífefnaverkfræði, lyfjafræði eða skyldra greina. Nýútskrifaðir eru hvattir til að sækja um.</p></li><li><p>Reynsla í sterílli vinnu og frumuræktun er æskileg.</p></li><li><p>Góð hæfni til að skrifa tæknilegar skýrslur og greina vísindaniðurstöður með forritum eins og Excel, JMP eða sambærilegu.</p></li><li><p>Mjög gott vald á ensku, bæði munnlegri og skriflegri.</p></li><li><p>Frumkvæði, skipulagshæfni og sterkur áhugi á lífvísindum.</p></li></ul><p></p><p><b>(English)</b></p><p></p><p>Alvotech is seeking a dedicated cell culture scientist to join our Upstream Process (USP) Research and Development (R&amp;D) team. As a scientist, you will play a crucial role in our USP team developing a small-scale bioreactor process for subsequent scale-up and transfer to a manufacturing environment for production of biosimilars.</p><p></p><p><b>Scope and responsibility:</b></p><ul><li><p>Mammalian cell culture at different USP stages spanning from shake flasks, rocker bioreactor, Ambr250 and up to 15L production bioreactors, finalized by cell clarification.</p></li><li><p>Geneal lab management on daily basis and operational work with bioreactor systems and associated analytical instruments.</p></li><li><p>Experimental execution and data collection, evaluation and analysis for effective upstream process development, optimization and characterization.</p></li><li><p>Technical report writing to feed into successful technology transfer to pilot/manufacturing scale and support of regulatory submission.</p></li></ul><p></p><p><b>Qualifications and skills</b></p><ul><li><p>University degree; BSc or MSc (Preferred) within biotechnology, biochemistry, biochemical engineering or related field.</p></li><li><p>Work experience in the field of biotechnology or comparable for 1-3 years is an advantage.</p></li><li><p>Hands on experience in aseptic techniques, cell culture in bioreactor systems and cell clarification is desirable.</p></li><li><p>Strong ability to analyze and evaluate scientific data using relevant software’s such as Excel, JMP or comparable.</p></li><li><p>Strong documentation skills for technical report writing with great organizational skills and attention to detail.</p></li><li><p>Excellent command of the English language, both verbal and written, with the ability to communicate fluently.</p></li><li><p>High interest and understanding within the field of biopharmaceutical development and associated GMP principles.</p></li><li><p>Scientific mindset, solution oriented, great team player with good adaptability and positive attitude.</p></li><li><p>Flexibility and able to support lab activities in evenings and weekends, if required.</p></li></ul><p></p><div><div><p><b>What we offer:</b></p><ul><li><p>An inspiring challenge to work with great co-workers on ambitious projects that change people&#39;s lives.</p></li><li><p>The chance to be a part of a global and fast-growing company.</p></li><li><p>An international work culture that encourages diversity, collaboration and inclusion.</p></li><li><p>Positive, flexible, and innovative work environment.</p></li><li><p>Support for personal growth and internal career development.</p></li></ul></div></div><div><div><ul><li><p>Company social events and milestone celebrations.</p></li><li><p>Excellent in-house canteen and coffee house.</p></li><li><p>Exercise and wellbeing support for full-time employees.</p></li><li><p>On-site shower facility.</p></li><li><p>Transportation grant towards eco-friendly modes of travel for full-time employees.</p></li><li><p>Internet at home for full-time employees</p></li></ul><p></p><p><b>Why Alvotech</b></p><p>At Alvotech, we are passionate about improving lives by increasing access to affordable biologics. We’re purpose-driven and committed to fostering an inclusive and diverse working environment that encourages curiosity, ingenuity and simplicity. We want our employees to feel inspired in their careers, challenged by interesting and meaningful work and empowered to succeed in an agile environment.</p><p></p><p>True to our Icelandic roots, we also believe that integrity, gender equality, and fairness are foundational. We strive to bring together the brightest minds regardless of backgrounds and beliefs, to deliver to our partners and patients around the world. Let’s create a healthier world together, through affordable biologic medicines.</p></div></div><p></p>