Senior Medical Director, Asset Lead – Oncology (Neuroendocrine Tumors / Carcinoid Syndrome)

Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others.

POSITION SUMMARY:  

Crinetics is seeking an experienced oncology Medical Affairs leader to serve as Senior Medical Director, Asset Lead – Oncology (Neuroendocrine Tumors / Carcinoid Syndrome), reporting to the Executive Director, Medical Affairs. This role will provide Medical Affairs leadership for a complex oncology program within the Neuroendocrine Tumor (NET) landscape, requiring deep expertise in oncology clinical development, competitive data interpretation, and cross functional medical strategy. This individual will be responsible for shaping and executing Medical Affairs strategy across evidence generation, scientific exchange, and KOL engagement, ensuring alignment with Clinical Development, Regulatory, Commercial, Market Access, Compliance, and Legal functions. The role demands strong scientific credibility in oncology, the ability to interpret and translate complex oncology data, and comfort operating in data dense, competitive therapeutic environments. The Medical Director will lead initiatives that support both late stage development and commercialization, contribute to lifecycle planning, and ensure a clear, differentiated scientific narrative for Carcinoid Syndrome within the broader NET oncology landscape. The successful candidate will balance scientific leadership with strong cross functional collaboration to support improved outcomes for patients with NETs.

Essential Job Functions and Responsibilities:

These may include but are not limited to: 

• Provide Medical Affairs leadership for an oncology program within the Neuroendocrine Tumor (NET) indication, including Carcinoid Syndrome.
• Interpret and translate complex oncology clinical, translational, and real world data into clear Medical Affairs strategy.
• Partner closely with Clinical Development to support late stage oncology trials, registrational strategies, and post approval evidence generation.
• Lead Medical Affairs strategy in a competitive oncology landscape, including differentiation versus standard of care and emerging therapies.
• Support oncology focused regulatory interactions, scientific advisory boards, and major medical congress strategy.
• Co-develop and implement integrated Medical Affairs strategic and tactical plans for the lead oncology asset.
• Identify data gaps through cross functional collaboration and develop integrated oncology evidence generation plans, including RWE and outcomes research.
• Execute Medical Affairs strategic imperatives to enhance oncology scientific exchange and healthcare practitioner education.
• Provide scientific guidance and tactical execution for medical publications, medical education, medical communications, medical information, RWE, and HEOR.
• Work across the organization to develop and implement oncology focused publication strategies.
• Provide medical review and approval of abstracts, posters, presentations, and manuscripts for scientific accuracy, balance, and compliance.
• Ensure Medical Affairs evidence strategies support differentiation, access, and long-term value of the oncology asset.
• Develop and maintain strategic relationships with oncology KOLs, including NET specialists, GI oncologists, and oncology researchers.
• Lead and contribute to scientific advisory boards, steering committees, and subject matter expert engagements.
• Foster research collaborations with key oncology research centers in the U.S. and OUS.
• Engage with relevant professional societies and patient advocacy organizations in compliance with regulatory and corporate standards.
• Work closely with Clinical Development, Regulatory, Commercial, and Market Access teams across the oncology development and commercialization lifecycle.
• Support preparation of clinical sections of regulatory submissions and safety reporting in conjunction with Medical Affairs leadership.
• Partner with Commercial and Market Access teams to ensure Medical Affairs input into brand strategy and lifecycle planning, while maintaining scientific and regulatory integrity.
• Provide medical review or support approval of promotional and medical materials in compliance with corporate standards and industry regulations.
• Support the Medical Information function in responding to external oncology related inquiries.
• Develop, refine, and implement Medical Affairs policies, procedures, and SOPs.
• Partner with cross functional teams to develop IME/CME strategies and provide medical review of independent medical education grant applications.
• Maintain current knowledge of and compliance with all applicable laws, regulations, and guidance governing oncology Medical Affairs activities.
• Other duties as assigned

Education and Experience:

Required:

• Doctoral degree (MD, DO, PhD, PharmD, or equivalent) with relevant Medical Affairs experience.
• 13+ years of experience in Medical Affairs within pharmaceutical or biotechnology organizations.
• Significant Medical Affairs experience in oncology, including support of oncology clinical development and/or commercial stage oncology assets.
• 5+ years of proven success in Medical Affairs leadership roles.
• 10+ years of experience in supervisory or people leadership roles.
• Demonstrated experience operating in data dense, competitive oncology environments.
• Experience building or scaling Medical Affairs capabilities in a growing organization.
• Broad working knowledge of FDA requirements, oncology regulatory standards, industry compliance, clinical trial design, publication strategy, and medical information processes.
• Deep understanding of evidence-based medicine, oncology outcomes research, and disease management principles.
• Excellent written, verbal, and interpersonal communication skills with demonstrated success in cross functional environments.
• Strong judgment, organizational skills, attention to detail, and ability to manage multiple priorities.
• Ability to thrive in a fast paced, growth-oriented biotech environment.
• High integrity and alignment with company core values.
• Familiarity with Medical Affairs platforms such as Veeva (PromoMats, MedComm, CRM) and ARISg or Argus safety systems preferred.

Preferred:

• Experience in Neuroendocrine Tumors (NETs), gastrointestinal oncology, or other solid tumor indications.
• Board Certified Oncologist
• Experience supporting late stage or post approval oncology assets.
• Experience contributing to oncology lifecycle management and differentiation strategy.

Physical Demands and Work Environment:

Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities.

Travel:

Travel may be required up to 30% of your time, and ability to travel globally as needed.

The Anticipated Base Salary Range: 

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process.

Equal Opportunity Employer:

Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws.

Salary Range

The salary range for this position is: $293000 - $366000.

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.