(Sr.) Manager, Clinical Supply Chain

<div class="content-intro"><p>Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation.</p> <p>Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs.</p> <p> </p></div><p><strong>Description of Role</strong></p> <p><span class="TextRun SCXW9857805 BCX0" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW9857805 BCX0">Centessa</span><span class="NormalTextRun SCXW9857805 BCX0"> is seeking a (Sr.) Manager, Clinical Supply Chain to oversee </span><span class="NormalTextRun SCXW9857805 BCX0">end-to-end</span><span class="NormalTextRun SCXW9857805 BCX0"> planning, execution, and maintenance of uninterrupted clinical supply, including IP, comparators, and ancillary materials. This role ensures compliance with </span><span class="NormalTextRun SpellingErrorV2Themed SCXW9857805 BCX0">GxP</span><span class="NormalTextRun SCXW9857805 BCX0"> requirements, study timelines, and budgets while partnering </span><span class="NormalTextRun SCXW9857805 BCX0">cross functionally</span><span class="NormalTextRun SCXW9857805 BCX0"> with Clinical Operations, CMC, Quality, Regulatory, Finance, and external vendors. Reporting to the Senior Director, Clinical Supply Chain, the individual will build strong relationships with internal teams and </span><span class="NormalTextRun SCXW9857805 BCX0">third-party</span><span class="NormalTextRun SCXW9857805 BCX0"> suppliers to align </span><span class="NormalTextRun SCXW9857805 BCX0">objectives</span><span class="NormalTextRun SCXW9857805 BCX0"> and ensure successful trial execution. Key responsibilities include managing clinical forecasts, inventory systems, and IRT tools with strong attention to detail and daily operational oversight.</span></span><span class="EOP SCXW9857805 BCX0" data-ccp-props="{}"> </span></p> <p><strong>Key Responsibilities</strong></p> <p><strong><span data-contrast="auto">Clinical Supply Planning & Execution: </span></strong><span data-ccp-props="{}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1"><span data-contrast="auto">Lead development and execution of clinical supply strategies for early- to mid-phase clinical trials (Phase 1–3 as applicable).</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Own clinical supply plans, demand forecasts, and inventory strategies aligned with protocol requirements and enrollment projections.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Manage packaging, labeling, distribution, and resupply activities for investigational products and comparators.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Ensure on-time delivery of clinical supplies to depots and clinical sites globally.<span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335559740":240}"> </span></li> </ul> <p><strong><span data-contrast="auto">Vendor & External Partner Management:</span></strong><span data-ccp-props="{"201341983":2,"335559685":360,"335559740":23}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1"><span data-contrast="auto">Collaborate with Quality, Clinical, CMC and external CDMOs to develop and approve clinical labels.</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1">Manage CDMO packaging/labeling schedules to ensure availability of clinical supplies.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1">Interact regularly with third-party providers to manage logistics & licenses required to ship materials from manufacturing to bulk storage facilities, courier depots and investigator sites.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1">Work with CMC and QA to facilitate document transfer required for CTM/QP release by CDMOs</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1">Manage and track clinical supply inventory either manually or through an Interactive Response Technology (IRT) system.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="5" data-aria-level="1">Manage Product Recovery pending investigation of CTM from investigator sites as needed.<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong><span data-contrast="auto">Collaboration:</span></strong><span data-ccp-props="{"201341983":2,"335559685":360,"335559740":23}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="11" data-aria-level="1"><span data-contrast="auto">Effectively collaborate and communicate across multiple functional areas, bringing a sufficient breadth of knowledge.</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="11" data-aria-level="1">Monitor shelf-life and expiry dating and coordinate retest extension with analytical team to ensure continuous supply.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="11" data-aria-level="1">Manage investigation, reporting and communication of outcomes from temperature excursions and product complaints.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="11" data-aria-level="1">Author Pharmacy Manuals for clinical studies, as needed </li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="11" data-aria-level="1">Represent Supply Chain in Clinical and CMC Sub Team meetings<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong>Qualifications</strong></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1"><span data-contrast="auto">Bachelor’s degree in engineering or science is required.</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">5-8 years of biotech/pharma industry experience in clinical <span data-contrast="auto">supply</span><em><span data-contrast="auto"> with international experience</span></em><span data-contrast="auto"> is required</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Experience in all aspects of clinical supply chain as well as a deep understanding of GMP/GDP</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Requires a strong understanding of managing groups, CMOs and CDMOs </li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Experience with blistering and walleting packaging processes preferred</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Proven background in working with small molecule modality required</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Experience operating within a commercial drug product environment preferred</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Strong organizational, analytical, decision-making and interpersonal skills</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Ability to work independently in a fast-paced dynamic environment</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Demonstrated ability to coordinate CDMO activities in the development and commercialization of pharmaceutical products</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Excellent organizational skills, project management skills and detail-orientated leadership approach</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="16" data-aria-level="1">Ability to thrive in a small company culture and assist in creating and implementing processes.<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong><span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}">Compensation</span></strong></p> <p><span data-contrast="auto">The annual base salary range for the Manager, Supply Chain position is $120,000 - $157,000. </span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">The annual base salary range for the Senior Manager, Supply Chain position is $145,000 - $190,000.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.</span><span data-ccp-props="{}"> </span></p> <p><strong>Work Location</strong></p> <p><span class="TextRun SCXW68217638 BCX0" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)">The (</span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)">Sr.) Manager</span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)">, Clinical Supply Chain</span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)"> role is a remote role based in the US, with occasional travel</span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)"> (up to </span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)">20%)</span><span class="NormalTextRun SCXW68217638 BCX0" data-ccp-parastyle="Normal (Web)">.</span></span><span class="EOP SCXW68217638 BCX0" data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335557856":16777215,"335559738":0,"335559739":360,"335559740":240}"> </span></p> <p><strong>POSITION:</strong> Full-Time, Exempt</p> <p> </p><div class="content-conclusion"><p>EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.</p> <p><strong><span class="break-words tvm-parent-container">Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.</span></strong></p></div>