COMPANY:
At BioCryst, we share a deep commitment to improving the lives of people living with hereditary angioedema (HAE) and other rare diseases. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and injectable protein therapeutics, led by the efforts of our team of expert scientists in our Discovery Center of Excellence in Birmingham, Alabama. Our global headquarters is in Durham, North Carolina and our employees span the globe across sites in multiple countries. We are proud of our culture of engagement and accountability that rewards people for innovative thinking and achievement of key objectives. For more information, please visit our website at www.biocryst.com or follow us on LinkedIn and Instagram.
JOB SUMMARY:
The Sr. Manger, Business Systems is a technical lead individual contributor and technical Oracle Fusion Cloud SME responsible for maximizing the value, stability, and scalability of Oracle Fusion Cloud ERP, Procurement, HCM, SCM, Supply Planning, and related modules within a regulated life sciences environment. This role provides hands-on techno-functional leadership, partnering with Managed Service Providers (MSPs), internal IT peers, and Finance, Procurement, Supply Chain, HR, and Quality stakeholders to successfully deliver enhancements and lead technical workstreams. #LI-REMOTE
ESSENTIAL DUTIES & RESPONSIBILITIES:
- Configure, optimize, and enhance Oracle Fusion ERP, Procurement, HCM, SCM and Supply Planning modules.
- Serve as the Oracle technical lead working with teams to build Oracle Fusion integrations with systems like Workday, Veeva, OneStream, and Concur using integration tools such as OIC and Boomi.
- Manage quarterly updates, regression testing cycles, and change-control activities within a GxP-regulated environment.
- Partner with IT, Finance, Supply Chain, HR, Quality and external partners to translate requirements into scalable Oracle solutions.
- Lead complex, cross-functional technical projects, including integrations and system expansions.
- Maintain documentation, SOPs, technical specifications, and audit readiness.
- Govern Fusion security, role-based access, and segregation-of-duties standards.
- Resolve incidents and service requests, conduct root-cause analysis, and implement long-term fixes.
- Monitor system performance, SLAs, KPIs, and user adoption.
- Provide technical leadership on Oracle integrations using OIC, OTBI, BI Publisher, and APIs.
- Maintain proactive, consistent communication with cross-functional business stakeholders.
- Ensure alignment between MSP support activities and business priorities.
- Provide day‑to‑day oversight of system integrators, SaaS vendors, and Managed Service Providers (MSPs) supporting Oracle Fusion and related enterprise platforms.
- Identify, assess, and prioritize opportunities to improve operational efficiency and business outcomes through technology.
- Lead technical discussions translating business requirements into technical solutions
- Co-ordinate with teams during UAT cycles to resolve issues
- Support continuous improvement by assessing existing processes and recommending optimizations.
- Manage and deliver small technology projects within the G&A portfolio.
- Manage and enhance vendor relationships with oversight of SLAs and support obligations.
- Manage and partner with external vendors to deliver Oracle Fusion enhancements, integrations, and upgrades while ensuring adherence to GxP, SOX, and 21 CFR Part 11 requirements.
- Lead cross‑functional project workstreams involving IT, Finance, Procurement, Supply Chain, HR, Quality, and external partners to support clinical, commercial, and corporate operations.
- Manage vendor and internal resources across concurrent initiatives, ensuring alignment to business priorities, validation requirements, and change‑control processes.
- Communicate technology updates and impacts affecting G&A business areas.
- Create functional and design documentation, system standards, and procedures for G&A systems.
- Follow project methodology, SDLC and change control processes to implement solutions
- Ensure compliance with applicable laws, IT controls, regulatory guidelines, and data-governance standards.
- Support audits, security assessments, and compliance activities related to G&A applications and data.
- Support Audit requirements for SOX, CFR Part 11, and IT compliance.
- Able to work flexibly across other technological platforms and cross-functional business areas when required.
EXPERIENCE & QUALIFICATIONS:
- Bachelor's degree or equivalent in Business, Scientific or Technical discipline is required.
- 8 years experience working in related technical field with minimum 3 years of hands-on experience with Oracle Fusion Cloud, or equivalent combination of education and experience.
- Experience designing and/or managing Oracle Fusion modules including Financials, SCM, Procurement, and HCM.
- Demonstrated experience managing third‑party vendors, system integrators, and MSPs in support of enterprise ERP and G&A systems within a biotech, pharmaceutical, or life sciences environment.
- Proven ability to lead cross‑functional, matrixed project teams spanning IT, Finance, Procurement, Supply Chain, HR, and Quality to deliver regulated enterprise system initiatives.
- Experience managing vendor activities across system implementation, enhancement, validation, and post‑go‑live support phases.
- Strong background in collaborative project execution, including requirements definition, solution design, UAT coordination, deployment, and stabilization in GxP‑regulated environments.
PREFERRED
- Experience in GxP, SOX, and 21 CFR Part 11 environments strongly preferred.
- Experience managing Oracle Fusion implementation or enhancement partners within biotech or pharmaceutical organizations, including governance of SLAs, KPIs, and delivery milestones.
- Familiarity with vendor change management, validation documentation, and audit support in regulated life sciences environments.
- Experience supporting enterprise systems used across clinical, manufacturing, supply chain, and commercial operations.
- Strong preference for candidates with modern integration platforms experience such as Boomi, OTBI, security/role design, OIC, and BI Publisher.
- Experience in preparing documents for ITGC
- Experience managing Veeva change control and deviation.
- Experience working in the life sciences industry.
The statements in this position description are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. The manager may assign additional responsibilities and assignments from time to time.
BioCryst is an equal opportunity employer and is committed to providing equal employment opportunities without regard to age, race, religion, sex, sexual orientation, gender identity, national origin, Veterans status, disability and/or other protected class characteristics. Additionally, BioCryst is committed to achieving its business objectives in compliance with all federal, state and local law.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.