Specialist/Senior Specialist, Immunohistochemistry

<div class="content-intro"><p><strong><u>Company Overview</u></strong></p> <p><span data-olk-copy-source="MessageBody">Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.</span></p></div><p><strong><u>Position Overview</u></strong></p> <p>The Immunohistochemistry Specialist/Senior Specialist will be central to advancing our drug development pipeline. This is a fast paced highly collaborative position which will be key to speeding medicines to patients. You will work cross functionally supporting pre-IND candidates through late-stage development collaborating with internal and external partners.</p> <p><strong><u>Responsibilities</u></strong></p> <ul> <li>Perform routine microtomy and staining of single/multi-plex Immunohistochemistry and RNA-ISH.</li> <li>Independently design, develop, guide, troubleshoot and validate IHC assay development for lead candidate molecules.</li> <li>Source, procure, and inventory FFPE tissue blocks for project and banking needs.</li> <li>Use a comprehensive electronic notebook and inventory system to record specimens, reagents, and experimental details.</li> <li>Perform full slide scanning maintaining an image and slide inventory system</li> <li>Maintain laboratory supplies and reagents. Participate in general lab upkeep.</li> </ul> <p><strong>Data analysis and interpretation:</strong></p> <ul> <li>Independently and with supervision interpret, understand and communicate complex scientific data to guide rapid decision making.</li> <li>Leverage expertise to enable decision making within team and cross-functionally.</li> </ul> <p><strong>Project collaboration:</strong></p> <ul> <li>Operate independently and collaboratively within cross-functional teams to design, plan and execute experiments aimed at advancing drug development projects.</li> <li>Partner and collaborate with colleagues from diverse scientific disciplines, including chemistry, pathology, biomarker, pharmacology, and translational medicine to rapidly achieve project goals.</li> <li>Collaborate with facilities and EHS to ensure optimal functionality of our lab space and adherence to safety guidelines.</li> <li>Fearlessly represent IHC team in project team meetings.</li> </ul> <p><strong>Documentation and reporting:</strong></p> <ul> <li>Maintain meticulously detailed and accurate electronic laboratory notebooks documenting experimental procedures, results, and conclusions.</li> <li>Prepare and present research findings to internal cross-functional teams and contribute to project updates providing histology and assay expertise.</li> </ul> <p><strong>Continuous learning and development:</strong></p> <ul> <li>Readiness and excitement for exploring new avenues and developing new assays in a fast-paced environment.</li> <li>Stay informed about the latest advancements in techniques for evaluating targeted therapeutics.</li> <li>Proactively seek opportunities for professional development.</li> <li>Contribute to and support the scientific growth of the research team.</li> </ul> <p><strong><u>Qualifications</u></strong></p> <ul> <li>Bachelor’s degree in a life sciences field.</li> <li>Minimum of 5 years of extensive experience performing histology and assay development in a drug discovery setting including multi-target and multi-species assays in preclinical drug development.</li> <li>Certified histotechnician (HT) or histotechnologist (HTL) highly desired.</li> </ul> <p><strong><u>Knowledge and Skills</u></strong></p> <ul> <li>Experienced immunohistochemistry assay development scientist.</li> <li>Familiarity with several IHC platforms including BondRX along with general IHC core instrumentation.</li> <li>Ability to prioritize and balance multiple projects simultaneously.</li> <li>Previous experience in antibody-based therapeutics or oncology drug discovery is preferred.</li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="title">Washington State Pay Range</div><div class="pay-range"><span>$98,946</span><span class="divider">—</span><span>$136,192 USD</span></div></div></div><div class="content-conclusion"><p><strong><u>E/E/O</u></strong></p> <p>Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.</p> <p><strong><u>E-Verify</u></strong></p> <p>Immunome, Inc. is a participant in E-Verify. Please review the following notices: <a href="https://immunome.box.com/s/bopxukipfidxjscs4bjxt75f90bvpppk" target="_blank">E-Verify Participation Poster</a> | <a href="https://immunome.box.com/s/r51g9subw1wqni9xkutbl6up635sjr8e" target="_blank">Right to Work Poster (English)</a> | <a href="https://immunome.box.com/s/r3ekbimwh988my9vzl76tnlbg60zvh9u" target="_blank">Right to Work Poster (Spanish)</a>.</p></div>