Senior Scientist, Molecular Design

Terray Therapeutics·
Remote
1w ago
Full-timeSeniorIT
$160K - $240K/yr(estimated)

Description

<meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Position Summary:&nbsp;</strong></b><span style="font-size:10pt;white-space:pre-wrap;">Terray is currently seeking a motivated, creative, and experienced scientist to join our molecular design (MoDe) group. As part of the Computational and Data Sciences (CDS) team, the candidate will help drive hit validation and advance programs through hit‑to‑lead by using our unique chemical datasets and integrated wet‑lab + computational technologies. A hallmark of this role is the close, day‑to‑day partnership with our medicinal chemistry, biology, and ML teams. MoDe scientists work hand‑in‑hand with wet‑lab colleagues throughout each design–make–test cycle, ensuring fast experimental feedback, shared problem‑solving, and seamless connection between computational design and laboratory execution. Crucial for this execution is collaboration with machine learning and data science teams in CDS. </span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">The core responsibilities of this position are: </span></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Design small molecules with in-house, high-throughput computational tools using both structural models and ligand-based data from our proprietary screening platform</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Lead chemistry efforts for multiple internal pipeline and partnered projects with ownership and clear communication of design strategies</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Manage external synthetic chemistry team(s) to effectively prioritize work to reach project goals</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Utilize Terray chemical technologies to design focus libraries to drive small molecule programs toward lead optimization</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Collaborate on development and evaluation of models and generative tools for compound design with the machine learning team</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Communicate molecular design strategy and outcomes to teams across the company</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Experience and Qualifications:&nbsp;</strong></b><span style="font-size:10pt;white-space:pre-wrap;">Part of Terray’s success is nurtured by a hands-on work environment where everyone is accountable, vested in a vision of excellence, and actively taking part in the success of the business. Terray supports a positive work environment where employees can feel engaged,&nbsp;recognized&nbsp;and empowered to be creative.&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><i><em style="font-size:10pt;white-space:pre-wrap;">Required Qualifications:</em></i><span style="font-size:10pt;white-space:pre-wrap;">&nbsp;</span></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">BS/MS/Ph.D&nbsp;in computational, organic, or medicinal&nbsp;chemistry&nbsp;with 4+ years of industry experience&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Experience&nbsp;with&nbsp;the application of&nbsp;ligand- and structure-based&nbsp;computational tools&nbsp;for&nbsp;molecular design&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Fluent in&nbsp;optimization of&nbsp;ADME&nbsp;and&nbsp;safety issues&nbsp;with the ability&nbsp;to&nbsp;communicate&nbsp;team&nbsp;strategies&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Experience&nbsp;with&nbsp;triage&nbsp;of&nbsp;large data sets from virtual screens, DEL&nbsp;screens, and/or HTS&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Excellent communication skills with experience&nbsp;conveying&nbsp;medicinal&nbsp;chemistry results cross-functionally&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Proven, or developing,&nbsp;program leadership&nbsp;experience&nbsp;</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Familiarity&nbsp;with&nbsp;the&nbsp;management of external&nbsp;chemistry teams</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Compensation Details:</strong></b><span style="font-size:10pt;white-space:pre-wrap;">&nbsp;$160,000 - $240,000&nbsp;(annually) depending on experience; participation in the Company's option plan; 3%&nbsp;retirement safe harbor&nbsp;contribution;&nbsp;fully-paid&nbsp;medical, dental, vision,&nbsp;life&nbsp;and disability&nbsp;benefits.&nbsp;&nbsp;</span></p> <meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Company Overview:</strong></b><span style="font-size:10pt;white-space:pre-wrap;"> Terray Therapeutics is a venture-backed biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic chemistry, automation, and nanotechnology.&nbsp;We’re&nbsp;generating chemical data purpose-built to propel drug discovery into the information age — and&nbsp;we’re&nbsp;doing it on a larger scale and faster than has ever before been possible.&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Our closed loop system generates precise chemical datasets at unrivaled scale that work seamlessly with AI to systematically map biochemical interactions between small molecules and causes of disease. Iterative cycles of virtual molecular design and experimentation power AI and machine learning models, which in turn guide the next cycle of design. With a chemistry engine that measures billions of interactions daily and becomes increasingly precise with every cycle, we can answer an unprecedented array of questions — deriving insights that enable us to predictably create drugs for patients in need.&nbsp;</span></p>
Terray Therapeutics

Terray Therapeutics

BIOTECHNOLOGY

Spatially encoded screening and optimization platform

LocationCA - Monrovia
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