Description

Key Responsibilities and Activities<ul><li style="text-align:justify;">Design, develop, and execute cell-based bioassays to evaluate performance of investigative drugs (biologics)</li><li style="text-align:justify;">Stay updated with cutting edge discoveries and trends and contribute to the company’s R&D strategy to generate and test actionable development plans</li><li style="text-align:justify;">Identify emerging methods, tools, and biology approaches, and implement them when applicable</li><li style="text-align:justify;">Function as a key team member, and simultaneously train and supervise associates on the R&D team</li><li style="text-align:justify;">Collaborate closely with other scientists and research associates on the R&D team</li><li style="text-align:justify;">Contribute to work with external parties, including academic collaborators and CROs to create comprehensive capabilities for MoA, target validation and potency studies</li><li style="text-align:justify;">Write clear and concise research reports and ensure study documentation and update protocols to ELN</li><li style="text-align:justify;">Participate and contribute to internal discussions and meetings</li><li style="text-align:justify;">Present results to the project leadership team and management in an organized and timely manner</li></ul> Required Education, Experience, Skills and Competencies<ul><li style="text-align:justify;">Ph.D. in Cellular Biology, Immunology, or a relevant discipline </li><li style="text-align:justify;">At least 2 years of industry research experience</li><li style="text-align:justify;">Extensive experience working with different types of in vitro systems such as immune cells, epithelial cells, fibroblasts, endothelial cells, and other cell lines</li><li style="text-align:justify;">Strong background with cell-based assays to interrogate immune pathway activation, immune suppression, cytotoxicity, antibody mediated cell killing</li><li style="text-align:justify;">Broad skillset for target validation, potency evaluation and MoA interrogations is highly desired, including the use of tissue culture approach with multiple readouts, flow cytometry, ex-vivo studies, use of gene knockdown tools, conventional immunoassays, phosphorylation analysis and conventional pulldown assays.</li><li>Hands on ability to execute wet lab experiments, data processing, and ability to effectively communicate key scientific findings across the organization</li><li style="text-align:justify;">Ability to establish and maintain cooperative working relationships with co-workers and other stakeholders</li><li style="text-align:justify;">Ability to adjust to workload changes and prioritize competing demands</li><li style="text-align:justify;">Ability to balance the big picture and fine technical details</li><li style="text-align:justify;">Outstanding organizational, critical thinking, and problem-solving skills</li><li style="text-align:justify;">Excellent written and verbal communication skills</li></ul>

Senior Scientist, In Vitro Pharmacology

Description

DynamiCure

Pipeline