Senior Scientist I, Cancer Immunology

The Opportunity:

As a key player in our Cancer Immunology team, you will use your immuno-oncology expertise to help advance Revolution Medicines’ assets in preclinical and clinical development.

Responsibilities:

• Design, develop, validate and execute in vitro, in vivo, and ex vivo studies to address key translational questions and support immuno-oncology biomarker plans.

• Identify, evaluate and implement emerging technologies to enhance translational biomarker discovery and mechanistic understanding.

• Drive reverse translation efforts by formulating and testing hypotheses derived from clinical finding as appropriate to inform clinical development plans.

• Stay abreast of advances in tumor immunology and immunotherapy, identifying novel combination strategies and contributing to preclinical evaluation.

• Analyze, interpret, and communicate complex data effectively across internal cross-functional teams and at external scientific meetings.

• Represent Revolution Medicines at scientific conferences and other external engagements.

Required Skills, Experience and Education:

• D. in immunology, cancer biology, or a related discipline, with deep expertise in tumor immunology, immuno-oncology biomarkers, and/or immunotherapy.

• Proven track record of research excellence, evidenced by high-impact publications.

• Expertise in in vivo model design to evaluate the efficacy and mechanisms of action of therapeutic agents and enable biomarker discovery, both internally and via contract research organizations.

• Strong technical expertise in immunology techniques including multi-parameter flow cytometric analyses, primary human cellular/tissue-based functional assays, cell biology and molecular biology to guide/inform mechanism of action and biomarker discovery.

• Strong problem-solving skills and ability to independently oversee scientific projects, rigorously analyze and interpret scientific data while maintaining attention to detail.

• Excellent written and verbal communication skills. Thrives in a fast-paced, collaborative, interdisciplinary team setting.

• 4+ years of relevant biotech or pharmaceutical industry experience in oncology drug discovery and development.

Preferred Skills:

• Hands-on experience with humanized mouse models is desirable.

• Familiarity with multiomics analyses and integrating computational insights into experimental designs.

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