Description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a Senior Research Associate to join our Antigen Science team and serve as a core technical resource for the whole group. You will be responsible for the day-to-day production of antigens that support antibody discovery, engineering, and assay development, including antigen expression, purification, DNA scale-up, and routine quality control. You will execute established workflows reliably and with high quality, and you will help the team keep reagent production moving so that colleagues across discovery and assay development receive what they need on schedule.

This is onsite in Bothell, WA.

Responsibilities

Carry out antigen purification using affinity, ion-exchange, and size-exclusion chromatography on FPLC or similar systems, following established protocols.
Scale up plasmid DNA preparations to support expression campaigns, ensuring quality and yield.
Perform recombinant antigen expression in mammalian cells, including both transient and stable expression,
Perform routine antigen quality control, including SDS-PAGE, Western blotting, and other standard analytical assays, and record and report results.
Maintain detailed, accurate laboratory records, inventory, and reagent batch documentation.

Qualifications

Senior Research Associate, Protein Sciences

Description

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