Senior Principal Scientist – Chemical Biology & Proximity-Based Therapeutics
Amgen
This listing was originally posted on Amgen's careers page. Formulate is an equal opportunity job aggregator and is not involved in the hiring process. Where salary information is estimated, it is derived from BLS industry benchmarks and may differ from actual compensation.
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Upgrade to Pro — $25/moAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Let’s do this. Let’s change the world. Amgen’s Induced Proximity Platform (IPP) is advancing a growing portfolio of therapeutic opportunities that leverage proximity biology to access previously undruggable targets. Through the discovery of small molecules that induce or stabilize protein–protein interactions, IPP is expanding the range of mechanisms and targets addressable by drug discovery.
We are seeking an exceptional Senior Principal Scientist to lead discovery efforts at the intersection of chemical biology, induced proximity, and phenotypic drug discovery. This role will focus on molecular glue discovery in disease-relevant systems, combining phenotypic screening, chemical genetics, and mechanistic biology to uncover novel therapeutic opportunities.
Opportunity
Within IPP, this role will contribute to advancing molecular glue discovery and broader induced proximity approaches through integrated phenotypic and mechanism-driven strategies.
The successful candidate will:
Key Responsibilities
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications:
Doctorate degree in Chemical Biology, Cell Biology, Biochemistry, Pharmacology, or related field [and relevant post-doc where applicable] and 3 years chemical biology and small molecule discovery, with experience in proximity-based mechanisms, molecular glues, or related areas experience
OR
Master’s degree in Chemical Biology, Cell Biology, Biochemistry, Pharmacology, or related field and 6 years of chemical biology and small molecule discovery, with experience in proximity-based mechanisms, molecular glues, or related areas experience
OR
Bachelor’s degree in Chemical Biology, Cell Biology, Biochemistry, Pharmacology, or related field and 8 years of chemical biology and small molecule discovery, with experience in proximity-based mechanisms, molecular glues, or related areas experience
Preferred Qualifications:
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
.Salary Range
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