Senior Portfolio & Delivery Manager

<p>Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.</p> <p><strong>The Opportunity:</strong></p> <p>The Senior Manager Portfolio & Delivery advances PMO maturity while ensuring disciplined execution of business system implementations and sustainment initiatives across the organization. This role is responsible for strengthening portfolio governance, modernizing visibility through advanced dashboarding and AI-enabled risk and capacity forecasting, and establishing structured intake and prioritization processes that enable predictable, scalable delivery. In addition, this position directly manages high-impact or strategically significant projects to ensure successful execution and model delivery excellence within the PMO framework. As the organization evolves beyond initial commercial launch, this position ensures IS operates with data-driven transparency, governance rigor, and execution discipline.  Key responsibilities include:</p> <p>Portfolio Strategy & Governance</p> <ul> <li> <p>Advance and formalize the PMO framework to support commercial launch and post-launch scale.</p> </li> <li> <p>Lead and continuously improve the intake process (business case quality, scoring, prioritization, gating). </p> </li> <li> <p>Lead development and continuous improvement of portfolio governance standards, controls, and reporting structures.</p> </li> <li> <p>Operationalize a structured intake process aligned to strategic priorities and resource capacity.</p> </li> <li> <p>Design and implement a transparent prioritization framework to guide investment decisions.</p> </li> <li> <p>Strengthen and advance the Technology Review Committee (TRC) through structured scoring, impact analysis, and trade-off visibility.</p> </li> <li> <p>Shift governance from reactive coordination to proactive decision enablement.</p> </li> </ul> <p>Portfolio Visibility & Predictive Insights</p> <ul> <li> <p>Modernize Project Portfolio Dashboards to provide executive-level visibility into delivery health.</p> </li> <li> <p>Incorporate AI-enabled risk prediction, capacity modeling, and planning analytics.</p> </li> <li> <p>Develop forward-looking forecasting models to support budget and resource planning.</p> </li> <li> <p>Provide leadership with actionable insights on portfolio risk, constraints, and trade-offs.</p> </li> </ul> <p>Project Management & Delivery Leadership</p> <ul> <li> <p>Directly manage complex, high-visibility, or cross-functional business system implementations.</p> </li> </ul> <ul> <li> <p>Lead projects from initiation through planning, execution, go-live, and stabilization.</p> </li> <li> <p>Develop project plans, resource strategies, and risk mitigation approaches.</p> </li> <li> <p>Monitor scope, budget, timelines, and dependencies in alignment with PMO standards.</p> </li> <li> <p>Facilitate executive-level status reporting and stakeholder communication.</p> </li> <li> <p>Intervene proactively to stabilize projects at risk.</p> </li> </ul> <p>Delivery Oversight & Execution Discipline</p> <ul> <li> <p>Oversee active business system implementations and sustainment initiatives across the portfolio.</p> </li> <li> <p>Ensure consistent application of PMO standards, tools, and reporting across projects.</p> </li> <li> <p>Monitor cross-functional dependencies, capacity utilization, and execution risks.</p> </li> <li> <p>Partner with functional IS leaders to align delivery plans with available resources.</p> </li> <li> <p>Drive continuous improvement in delivery predictability and operational performance.</p> </li> <li> <p>Serve as a power user for PPM tools (e.g. Smartsheet). Automate reporting where feasible; document processes and run training to uplift adoption. </p> </li> </ul> <p>Strategic Impact</p> <ul> <li> <p>Predictable, scalable delivery through a modern PMO operating model.</p> </li> <li> <p>Improved portfolio clarity and executive decision-making.</p> </li> <li> <p>Stronger alignment between strategic priorities and resource allocation.</p> </li> <li> <p>Reduced delivery volatility and reactive firefighting.</p> </li> <li> <p>Increased leadership confidence in IS planning and execution.</p> </li> </ul> <p><strong>Required Skills, Experience and Education:</strong></p> <ul> <li> <p>Bachelor’s degree in Business, Information Systems, Science, Engineering, or related field</p> </li> <li> <p>7+ years of progressive experience in portfolio management, PMO leadership, and direct project management.</p> </li> <li> <p>Demonstrated success leading complex, cross-functional system implementations.</p> </li> <li> <p>Experience advancing PMO maturity in a scaling organization.</p> </li> <li> <p>Proven ability to design governance frameworks and prioritization models.</p> </li> <li> <p>Strong experience with portfolio reporting tools and dashboard development.</p> </li> <li> <p>Exceptional executive communication and stakeholder management skills.</p> </li> </ul> <p><strong>Preferred Skills:</strong></p> <ul> <li> <p>Experience in biotechnology, life sciences, or regulated environments.</p> </li> <li> <p>Familiarity with AI-enabled analytics or predictive portfolio tools.</p> </li> <li> <p>PMP, or equivalent certification.</p> </li> <li> <p>Lean 6-sigma certification.</p> </li> <li> <p>Experience supporting or leading structured governance forums such as a Technology Review Committee. </p> <p class="p1"><span style="color: rgb(255, 255, 255);">#LI-Hybrid  #LI-YG1</span></p> </li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="description"><p>The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.</p> <p>Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.</p> <p>Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.</p> <p>Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our <a href="https://www.revmed.com/ccpa-notice">CCPA Notice</a> and <a href="https://www.revmed.com/privacy-policy">Privacy Policy</a>. For additional information, please contact <a href="mailto:privacy@revmed.com">privacy@revmed.com</a>.</p></div><div class="title">Base Pay Salary Range</div><div class="pay-range"><span>$164,000</span><span class="divider">—</span><span>$205,000 USD</span></div></div></div><div class="content-conclusion"><hr> <p><em>We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.</em><br><em> </em><br><em>Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official <strong>@revmed.com</strong> email address.</em><br><em> </em><br><em>If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to <span style="color: rgb(35, 111, 161);"><strong>careers@revmed.com</strong></span> so we can share these impersonations with our IT team for tracking and awareness.</em></p> <hr> <p> </p></div>