Senior Manager, Medical Affairs External Funding Operations

The Opportunity

The Senior Manager, Medical Affairs External Funding Operations will serve as the operational owner of Revolution Medicines' external funding program supporting Medical Affairs objectives, with primary responsibility for the infrastructure, governance processes, systems, and operational strategy that enable compliant and effective management of Independent Medical Education (IME), Patient Advocacy, Charitable Donations, and other applicable external funding activities.

This individual will own and continuously evolve the operational framework supporting the end-to-end funding lifecycle, including request intake, review and governance processes, grants management systems, budget and portfolio tracking, contracting, payment processing, Letters of Agreement (LOAs), program tracking, reporting, and documentation. The Senior Manager will apply independent judgment to identify and resolve complex operational issues, partner with Medical Affairs, Legal, Compliance, Finance, and other stakeholders on matters requiring cross-functional input, and drive scalable process improvements as the external funding program evolves.

As a key partner to Medical Strategy teams and the Medical Affairs Grant Review Committee (GRC), this role will translate external funding data and program activity into actionable reporting and insights that support funding discussions, portfolio visibility, operational planning, and continuous improvement. The Senior Manager will own the operational cadence and materials supporting GRC meetings and maintain visibility into the status and timelines of RevMed-supported IME programs. This role requires strong program ownership, sound judgment, operational and analytical capabilities, attention to detail, and the ability to independently drive complex cross-functional initiatives in a fast-paced and evolving environment. Key responsibilities will include:

• Serve as the operational owner of Revolution Medicines' external funding program, including Independent Medical Education (IME), medical and patient advocacy sponsorships, memberships, corporate agreements, and charitable donations, ensuring scalable, consistent, and compliant execution across funding mechanisms.

• Own and continuously evolve the end-to-end operational framework for external funding, including submission, review, approval, contracting, payment processing, reconciliation, program tracking, and closeout; identify process gaps and implement improvements in partnership with relevant cross-functional stakeholders.

• Own the company's grants management platform, including system administration, workflow configuration and optimization, data integrity, reporting capabilities, and internal and external user experience; serve as the primary business partner to the grants management system vendor to troubleshoot issues and evaluate and implement system enhancements.

• Assess funding request submissions for operational completeness and eligibility for industry support and ensure requests are appropriately prepared for review by the applicable governance committee; identify and drive resolution of complex operational issues and engage Medical Affairs, Legal, Compliance, or other stakeholders when additional guidance or decisions are required.

• Manage the operational cadence for Medical Affairs Grant Review Committee (GRC) meetings, including development and distribution of agendas, preparation of funding and portfolio reports, development of presentation materials in partnership with Medical Affairs leadership, documentation of decisions, and coordination of follow-up actions.

• Partner with Finance to oversee grant and sponsorship budgets, track expenditures and commitments, reconcile payments, support financial reporting, and provide visibility into current and projected funding activity.

• Oversee and execute the Letter of Agreement (LOA) process for RevMed-supported IME programs, including continued refinement of the process, and coordinate with Commercialization Contracts, Legal, Compliance, Finance, Procurement, Accounts Payable, and external organizations to facilitate timely contracting, appropriate review and signature, funding execution, and archiving.

• Maintain comprehensive visibility into the portfolio of ongoing RevMed-supported IME programs, including key milestones, timelines, payments, and deliverables; proactively identify delays, risks, or dependencies requiring follow-up or escalation and coordinate timely internal launch announcements for enduring RevMed-supported IME programs.

• Maintain complete and inspection-ready documentation supporting internal audits, compliance monitoring, transparency reporting, and other applicable requirements.

• Analyze grants management system data and develop reports, dashboards, and portfolio views that provide Medical Strategy teams and the GRC with visibility into funding activity, budget utilization, program status, and relevant trends to support informed discussion, planning, and decision-making.

• Identify emerging operational needs, risks, and opportunities across the external funding portfolio and recommend and implement process, system, governance, or reporting enhancements that improve operational efficiency, scalability, and the user experience for internal and external stakeholders.

• Stay current on applicable industry guidance, regulations, and company policies related to external funding and incorporate evolving requirements into operational processes in partnership with Legal, Compliance, and other appropriate stakeholders.

• Support inspections, audits, and compliance reviews related to external funding activities and drive implementation of resulting operational improvements, as appropriate.

• Build productive relationships with external educational providers, medical societies, patient advocacy organizations, healthcare organizations, and other funding recipients to support effective program execution and issue resolution.

• Lead the development and continuous improvement of policies, SOPs, work instructions, process documentation, and training materials related to external funding operations.

Required Skills, Experience and Education:

• Bachelor's degree required.

• Approximately 5-7+ years of experience in Medical Affairs operations, medical education, grants management, healthcare compliance, or a related pharmaceutical/biotechnology function.

• Experience managing independent medical education (IME), medical and patient advocacy sponsorships, charitable donations, or related external funding programs within the life sciences industry, preferably in oncology.

• Working knowledge of applicable healthcare compliance requirements, including ACCME Standards for Integrity and Independence, PhRMA Code, Sunshine Act/Open Payments, and other relevant global regulations.

• Experience with grants management systems and associated workflows.

• Demonstrated experience independently owning complex cross-functional programs or operational processes, including identifying issues, developing recommendations, driving solutions through implementation, and managing multiple priorities simultaneously.

• Experience leading cross-functional processes involving Medical Affairs, Compliance, Legal, Finance, Accounts Payable, Procurement, and other stakeholders, with the ability to synthesize operational and portfolio data into clear insights and executive-ready materials that support planning and decision-making.

• Strong financial acumen, including budget management, payment tracking, and reconciliation.

• Excellent written and verbal communication skills with strong attention to detail.

• Proficiency with Microsoft Office applications and data reporting tools.

• Demonstrated ability to work independently while effectively collaborating across functions.

Preferred Skills:

• Strong program ownership and operational mindset, with exceptional attention to detail and a focus on scalable, sustainable processes.

• Excellent judgment and commitment to ethical, compliant decision-making.

• Ability to build collaborative relationships across diverse internal and external stakeholders.

• Customer-focused approach while maintaining appropriate compliance boundaries.

• Highly organized with the ability to manage competing priorities in a dynamic environment.

• Continuous improvement mindset with a focus on scalable, efficient processes.

• Dedication to improving the lives of those living with cancer and their caregivers.

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