Senior Director, Market Access National Accounts

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Senior Director, National Accounts (ESI/Cigna)- MASH

The Senior Director, National Accounts is responsible for leading Madrigal's engagement with key national payer and PBM accounts to optimize patient access, strengthen account performance, and support business objectives across the MASH portfolio.

This role reports directly to the Executive Director, National Accounts and serves as a senior strategic partner across National Accounts, Regional Account Directors, Market Access, Finance, Analytics, Trade, Specialty Pharmacy, and Field teams. The Senior Director translates payer dynamics, contract structures, access performance, and customer insights into clear strategies and execution plans.

As a senior leader, this individual will manage complex national account relationships, support contracting and financial performance objectives, and ensure payer wins translate into real-world access, utilization, and field execution.

Position Responsibilities:

•    Lead strategy and execution for priority national payer and PBM accounts, including development of short- and long-term account plans aligned to brand, access, and financial objectives.

•    Serve as the primary point of contact for assigned national accounts, engaging pharmacy, medical, formulary, population health, quality, and economic decision-makers.

•    Build trusted customer relationships that enable effective collaboration, negotiation, contracting discussions, and issue resolution.

•    Monitor account performance against contracted expectations, business plans, access objectives, and financial assumptions; identify risks, gaps, and opportunities for improvement.

•    Partner with the Executive Director, Pricing & Contracting, Value & Access, and Legal to support contracting strategy, rebate accuracy, contract alignment, gross-to-net performance, and financial reconciliation.

•    Analyze payer performance, utilization management, coverage quality, formulary alignment, pull-through, and operational access barriers to identify trends and systemic opportunities.

•    Partner closely with National Account Directors, Regional Account Directors, Sales, Trade, Patient Support Services to translate payer wins into field-level execution and remove barriers to patient access.

•    Develop national account performance updates, executive briefings, strategic recommendations, and customer-facing business reviews.

•    Share customer and market insights to inform messaging, tools, resource development, access strategy, and cross-functional execution plans.

•    Provide leadership, guidance, and best-practice sharing across National Accounts and cross-functional partners while demonstrating strong executive presence, accountability, and compliance.

Qualifications and Skills

• Bachelor degree required; advanced degree such as MBA, MPH, PharmD, or related discipline preferred.
• 12+ years relevant pharmaceutical or healthcare related work experience
• 6+ years of experience in Market Access, payer strategy, national account management, contracting, finance, analytics, or related pharma, biotech, payer, or health plan roles.
• Demonstrated experience managing national or large regional payer accounts, including PBMs and/or large commercial plans.
• Strong understanding of the U.S. payer landscape, formulary management, utilization management, payer contracting, rebate structures, gross-to-net, Specialty Pharmacy, reimbursement, and patient access pathways.
• Proven ability to manage complex customer relationships, influence cross-functional stakeholders, and translate data and market insights into actionable strategies.
• Experience supporting product launches, access strategy execution, business reviews, performance scorecards, and cross-functional reporting processes preferred.
• Strong executive communication, analytical rigor, financial and contracting acumen, collaboration, project management, and follow-through skills.
• Proficiency with Microsoft Office applications, including Excel and PowerPoint; familiarity with payer data, claims, CRM, specialty pharmacy, or access analytics platforms preferred.
• Role requires up to 30% domestic travel
• Excitement about Madrigal's vision and mission.

Madrigal offers a competitive Total Rewards strategy to attract and retain top talent and is inclusive of base pay, bonus, equity, and a generous benefits package. Full-time employees are eligible for base salary, bonus, equity, and a comprehensive benefits suite.

Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.    As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $264,000 - $323,000 per year.  We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.  

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. 

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. 

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. 

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. 

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. 

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.  

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to HR@madrigalpharma.com.