Senior Director, Alliance Management

THE OPPORTUNITY

Vir Bio is looking for a Senior Director, Alliance Management, to provide strategic leadership for a portfolio of high‑value external partnerships, including Vir Bio’s commercial hepatitis delta collaboration with Norgine across Europe, Australia, and New Zealand. This role operates with broad autonomy and accountability for alliance performance and value realization.

You will serve as a senior enterprise leader for certain alliances, partnering closely with cross‑functional executives to shape strategy, establish effective governance, and ensure disciplined execution across the alliance lifecycle. This role is accountable for maximizing the strategic, operational, and financial value of their portfolio of partnered assets through proactive leadership, risk management, and issue resolution.

As the primary executive interface for assigned partners, you will own alliance health, execution against Definitive Agreements (DAs), and long‑term relationship outcomes, including amendment strategy and exit planning.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

WHAT YOU'LL DO

• Provide strategic leadership for a portfolio of alliances spanning clinical collaborations, co‑development partnerships, and commercial agreements, with accountability for overall alliance performance and value delivery.
• Establish and lead fit‑for‑purpose governance models; chair and orchestrate joint governance forums and cross‑company teams to align priorities, enable decision‑making, and drive execution.
• Define and maintain a clear strategic intent and multi‑year operating plan for each alliance, ensuring alignment with Vir Bio’s portfolio strategy and regular communication to senior stakeholders.
• Serve as the senior point of accountability for partner relationships within the assigned portfolio, setting the tone for collaboration, trust, and performance; proactively address relationship risks and escalation topics.
• Own oversight of financial and non‑financial obligations, including leadership of quarterly partner financial reviews, forecasting, and variance analysis in close partnership with Finance.
• Ensure disciplined execution against all contractual obligations, including milestones, payments, supply commitments, and performance terms, with timely identification and mitigation of execution risks.
• Lead partner negotiations related to agreement amendments, extensions, and terminations, in collaboration with Legal, BD, and functional leadership.
• Anticipate and manage complex alliance challenges arising from contractual interpretation, strategic misalignment, or operational dependencies, applying sound judgment and enterprise perspective.
• Drive continuous improvement in alliance effectiveness by conducting structured alliance health assessments and translating insights into concrete actions that enhance value realization.

WHO YOU ARE AND WHAT YOU BRING

• BA/BS with 18+ years, MS/MBA with 16+ years, or PhD with 13+ years of progressive pharmaceutical or life sciences experience in senior leadership roles
• 8+ years of experience in Alliance Management and/or Partnering within a biotech or pharmaceutical organization, managing complex, high‑value partnerships.
• Proven experience leading alliances involving late‑stage development assets, with additional experience supporting commercial‑stage products and launches.
• Strong command of development, commercialization, and collaboration agreements, with the ability to interpret, negotiate, and operationalize complex contractual terms.
• Demonstrated ability to lead through influence in a highly matrixed environment and to partner effectively with senior executives across functions and organizations.
• Strong strategic, analytical, and problem‑solving capabilities, with consistent application of sound business judgment.
• Collaborative leadership style with the ability to build alignment, drive decisions, and hold teams accountable.
• Comfortable operating in a fast‑paced, evolving environment with high ambiguity and enterprise‑level visibility.
• Experience in the fields of infectious diseases and oncology preferred.