Scientist - Small Molecule Technology

<p><b><span style="font-size:14px">Job Description</span></b></p><p></p><p></p><ul><li><ul><li><p>Develop safe, robust, scalable, and efficient manufacturing processes for intermediate and Active Pharmaceutical Ingredients (APIs) suitable for both pilot plant and commercial scale production.</p></li><li><p>Performing literature search and identifying various synthetic routes for process development.</p></li><li><p>Promotes the use of novel experimental approaches within sub-function; routinely investigates/creates innovative processes, hypotheses and methodologies.</p></li><li><p>Knowledge of interpretation of structures using spectral techniques like NMR, IR &amp; Mass spectra.</p></li><li><p>Planning and Performing experiments as per process governance (Lab feasibility, Optimization, Pre-validation, CPP and Validation)</p></li><li><p>Performing What if studies, stress studies, holding time studies, Mass balance, recovery studies and scale up studies.</p></li><li><p>Encountering the process challenges on time and supporting production teams for scale up activities.</p></li><li><p>Handling of business critical / supply chain critical related investigational projects on fast track</p></li><li><p>Participate in brainstorming activity for the project in identifying scope of improvement</p></li><li><p>Responsible for making necessary scientific statutory documents for the lab execution of a given project</p></li><li><p>Designing experiments based on the project /business requirement in varying scale as per the needs</p></li><li><p>Perform data analysis, interpret the data of them and provide scientific rationale for the experiments</p></li><li><p>Support the next level manager in providing the cost estimates associated with R&amp;D project proposals</p></li><li><p>Summarize the experimental results and present to the next level managers for discussion</p></li><li><p>Prepare Technical project updates with precious data as per the business meeting requirement regularly</p></li><li><p>Knowledge on ICH guidelines.</p></li><li><p>Willingness to learn and apply new technology/ tools to meet process / business needs</p></li><li><p>Co-ordinate with Analytical, Process safety, Process engineering teams on the project discussions and support the need of them to drive the project</p></li><li><p>Utilization of electronics tools (Biovia eLN, GDMS, LIMS etc.,)</p></li><li><p>Partner closely with other CRD scientists, Process Engineers, Process Safety Chemists, Crystallization Technologists, Pilot Plant facility, Analytical, Formulation and manufacturing colleagues at Global Pfizer sites as required.</p></li><li><p>Responsible for instrument qualification across the CRD labs (coordination with instrumentation team, quality team)</p></li><li><p>Ensure compliance with cGMP /GSP procedures and practices</p></li><li><p>Ensure effective safety systems are implemented in the premises</p></li><li><p>Perform other tasks as per the dynamic business requirement</p></li></ul></li></ul><p></p><p><b>QUALIFICATION<span style="font-size:14px"> </span></b></p><ul><li><p>Ph.D in the field of Organic Chemistry.</p></li><li><p>Demonstrated capabilities and experience in performing chemical reactions, structure characterizations, basic understanding of chromatography, Crystallizations, Basic safety principles, Basic quality principles, basic understanding of analytical techniques.</p></li><li><p>Experience and demonstrated competencies in working with teams in a matrixed organization, building and nurturing relationships and effective engagement resulting in successful outcomes.</p></li><li><p>Candidate should have skill in preparing the technical reports and adherence to compliance.</p></li></ul><p>  <br />Work Location Assignment: On Premise</p><p><b> </b></p><p><b> </b></p><p><b> </b></p>&nbsp;&nbsp;<br>Work Location Assignment:&nbsp;On Premise<br><p style="text-align:inherit"></p><p style="text-align:left"><span><span><span><span><span><span><span><span><span>Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.</span></span></span></span></span></span></span></span></span></p><p style="text-align:inherit"></p><p style="text-align:inherit"></p>Research and Development<p></p><p></p>