Scientist, Pharmacokinetics

Job Description

Job Location:

West Point, PA

The Department of Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB) is seeking a bioanalytical scientist to join our End-to-End Regulated PK & ADA Bioanalytical group located at our research and development site in West Point, PA.  Experience in the field of quantitative bioanalysis of small molecules and biotherapeutics, leveraging LC-MS/MS and/or ligand binding methods in a regulated drug development environment, is highly preferred.  In this position, you will be responsible for developing bioanalytical methods for measuring biotherapeutics, such as small molecules, monoclonal antibodies, proteins, peptides and antibody-drug conjugates in support of Good Laboratory Practice (GLP) and clinical studies.

 

Main Responsibilities include but are not limited to:

• Method development, validation, and sample analysis for the quantitation of drug candidates in biological matrices (e.g., serum, plasma)

• Delivering high quality quantitative data in a timely manner to cross-functional collaborators.

• Effectively documenting, tracking, and communicating scientific findings and recommendations within cross-functional teams

• Contributing to establishing and maintaining bioanalytical lab operations including safety, compliance, automation and analytical instrumentation.

• Contributing to authoring of method development reports, test methods, qualification and validation reports, and study reports.

Education Minimum Requirements:

• B.A./B.S. in Biology, Immunology, Molecular Biology, Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with a minimum of 3 years of relevant experience

• Master’s Degree in Biology, Immunology, Molecular Biology, Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline with 1 to 2 years of experience

• undefined

Required Experience and Skills:

• Knowledge of the basic principles of regulated bioanalysis and Good Laboratory Practice (GLP)

• Good verbal and written communication skills

• Ability to follow procedures and thoroughly document experiments.

• Strong direct experience with LC-MS and/or ligand binding assay methodologies for quantitative and qualitative analysis of biotherapeutics

• Understanding of the drug discovery and/or development process and DMPK science

• Ability to work efficiently and multitask in a fast-paced environment

• Fosters team-based approach to research; committed to working synergistically and harmoniously with others

Preferred Experience and Skills:

• Experience with antibody drug conjugate (ADC) bioanalysis is advantageous.

• Understanding of immunogenicity and anti-drug antibody method development.

Required Skills:

Antibody Drug Conjugates (ADC), Bioanalysis, Biochemistry, Data Analysis, Data Visualization, Detail-Oriented, Drug Metabolism, Ethical Compliance, GMP Documentation, Good Laboratory Practices (GLPs), Immunoassays, Immunochemistry, Immunology, Immunotherapy, Ligand Binding Assay, Liquid Chromatography-Mass Spectrometry (LC-MS), Molecular Biology, Pharmacodynamics, Pharmacognosy, Pharmacokinetics, Pharmacotherapeutics, Sample Analysis, Small Molecule Screening

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The salary range for this role is

$87,300.00 - $137,400.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

04/23/2026

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.