Scientist II, Bioanalytics

THE OPPORTUNITY

Vir Biotechnology is seeking a detail-oriented, highly motivated Bioanalytical Scientist to join our Translational Development team.

In this role, you will develop and implement bioanalytical methods to support large-molecule programs at both preclinical and clinical stages. Responsibilities include designing and executing immunochemistry assays (e.g., ELISA, MSD, anti-drug antibody assays) and preparing samples for LC-MS/MS analysis. You will contribute to immunoassay development across multiple programs and analyze preclinical samples for drug concentrations and anti-drug antibodies.

This description outlines the primary responsibilities and requirements but is not exhaustive; additional related duties may be assigned as needed.

This position is based at our San Francisco headquarters, with an expectation of at least 4 days per week on site.

WHAT YOU'LL DO

• Develop and optimize bioanalytical methods to support large-molecule preclinical and clinical candidates, providing bioanalytical input across research and development stages.
• Plan and coordinate method development and sample analysis activities in alignment with program and development timelines.
• Troubleshoot and evaluate complex bioanalytical methods to identify and implement robust solutions.
• Prepare and characterize assay reagents using standard biochemical techniques (e.g., protein conjugation, concentration determination, UV/Vis spectrophotometry).
• Maintain thorough and timely documentation in electronic lab notebooks; compile, analyze, and interpret data.
• Present experimental plans and results in group and cross-functional settings to communicate assay development progress.
• Perform routine instrument maintenance, calibrations, and performance checks as needed.
• Collaborate closely with other assay development team members to achieve project and departmental goals.

WHO YOU ARE AND WHAT YOU BRING

• PhD with 1+ years, MS with 6+ years, or BS with 8+ years of relevant industry experience.
• Experience that combines hands-on laboratory work with project oversight; prior experience managing CROs for clinical and nonclinical assay development/validation is a plus.
• Demonstrated understanding of GLP/GCP principles as they pertain to sample handling and storage, bioanalytical assay development, sample analysis, and laboratory operations.
• Strong technical expertise with platforms used to characterize large-molecule therapeutics, including assays with complex handling and preparation (e.g., enzymatic, ligand-binding, cell-based assays, and LC-MS/MS assays) across a range of biological matrices (e.g., serum, plasma).
• Familiarity with PK/PD concepts and their application to assay design, selection, and range determination.
• Prior work in GCP/GLP/GMP environments is advantageous but not required.
• Prior work utilizing LC/MS/MS is advantageous but not required