Medical Director, Opthalmology

We are seeking an accomplished and visionary Medical Director to lead the clinical development of our ophthalmology programs at AAVantgarde. This role is central to shaping and executing our global clinical strategy, overseeing trials from first-in-human through Phase 3, and ensuring the scientific and medical integrity of our investigational products. As Medical Director, you will provide clinical leadership across all aspects of trial design and execution, including protocol development, feasibility assessments, site selection, and enrolment strategy. You will serve as the primary medical point of contact for internal teams, clinical sites, and external stakeholders, offering guidance on disease mechanisms, safety management, and regulatory compliance. A key part of your role will be building relationships with principal investigators and key opinion leaders, contributing to scientific dialogue and ensuring our programs remain at the forefront of innovation. You will lead medical data reviews, oversee safety assessments, and contribute to regulatory submissions and health authority interactions. This is a highly collaborative role that requires strategic thinking, scientific depth, and a strong understanding of the competitive landscape in ophthalmology and gene therapy.