Medical Director, Clinical Development

<meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><b><strong style="font-size:13.5pt;white-space:pre-wrap;">What You'll Do </strong></b></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Works cross-functionally to provide scientific and clinical leadership on activities including all aspects of clinical study planning, conduct, and read-out, lifecycle planning, scientific communication, and regulatory filings.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Provides expert opinion on the pathophysiology and diagnosis of disease, existing and emerging treatments and unmet medical needs to inform key medical and business decisions.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Conducts medical monitoring of clinical trials; writes protocols, informed consent documents; responds to questions from regulatory agencies, institutional review boards and ethics committees; reviews clinical data, case report forms and ensures final accuracy of clinical trial data for clinical study reports.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Conducts safety monitoring, oversees conduct of clinical sites for adherence to both company standards, and government/industry regulations (GCP/ICH); supports development of investigator brochures; trains investigators and travels to clinical sites to build relationships with investigators and study teams in support of study enrollment.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Institutes and continuously improves operating procedures ensuring best practices.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Establishes appropriate strategic partnerships with centers of excellence, advocacy groups and KOLs in the areas of scientific interest.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Collaborates closely with key stakeholders to ensure tight strategic integration of product development plans and strategies. Plans and develops content for advisory meetings with opinion leaders and for medical symposia.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Participates in review of medical materials to ensure content is medically appropriate and compliant with internal and external requirements.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Oversight of partnered clinical research operations (CRO) vendors.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Keeps up to date on current relevant therapeutic areas through familiarity with literature, attendance at meetings, conventions and professional associations.</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><b><strong style="font-size:13.5pt;white-space:pre-wrap;">What You'll Bring</strong></b></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">MD or equivalent, with a minimum of 3-5 years of biotech or pharmaceutical experience in oncology drug development. Oncology fellowship training and ABIM Oncology certification preferred.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team. Ability to establish and maintain effective working relationships.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Strong leadership skills and the ability to lead through example.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Strong understanding of clinical trials process with demonstrated ability to have designed and implemented programs and initiatives directed towards defined strategic objectives.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Early-stage development and regulatory experience preferable.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Excellent organizational skills with the ability to manage concurrent deliverables and work effectively in a challenging, milestone-driven environment.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Strong problem-solving skills with the ability to think and act strategically, anticipate roadblocks and map out next steps.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Demonstrated high level of integrity, ethics and professionalism.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Knowledge of scientific methods, research design and medical practices and procedures.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Excellent writing and oral presentation skills. Demonstrated ability to communicate scientific results.</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Ability to travel.</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><b><strong style="font-size:13.5pt;white-space:pre-wrap;">Total Rewards</strong></b></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="font-size:11.25pt;white-space:pre-wrap;">We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies.&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br><span style="font-size:11.25pt;white-space:pre-wrap;">The base salary range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position in the location for which the job is posted and does not include bonus, equity, or benefits. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience).</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="font-size:11.25pt;white-space:pre-wrap;">Our total rewards package that includes:&nbsp;</span></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Industry leading vacation and paid time off</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Exceptional medical, dental and vision benefits by country</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Zymelife health and wellness benefits</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Matching RRSP / 401K / Pension program</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Employee Share Purchase Program</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Employee Equity Program</span></li><li style="font-size:11pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:11.25pt;white-space:pre-wrap;">Paid time off to volunteer in your community</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><span style="font-size:11.25pt;white-space:pre-wrap;">This role is not eligible for relocation or immigration support.&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="font-size:11.25pt;white-space:pre-wrap;">All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="font-size:11.25pt;white-space:pre-wrap;">&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:11.25pt;white-space:pre-wrap;">NOTE TO AGENCIES:&nbsp;</strong></b><span style="font-size:11.25pt;white-space:pre-wrap;"> Zymeworks values our relationships with our recruiting partners. We only accept resumes from those partners who have been contracted with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract. &nbsp;</span></p> <meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:13.5pt;white-space:pre-wrap;">Company Description</strong></b><br><span style="white-space:pre-wrap;">Zymeworks is a publicly listed (NASDAQ:ZYME) clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeutics to improve the standard of care for difficult-to-treat diseases, including cancer, inflammation, and autoimmune disease. Zymeworks' suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop </span><span style="color:rgb(0,0,0);background-color:rgb(255,255,255);font-size:11.25pt;white-space:pre-wrap;">antibody-based therapeutic candidates</span><span style="white-space:pre-wrap;">. We are a global company headquartered in Vancouver, BC, with operations in Bellevue, WA, Dublin, Ireland, and Singapore.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="white-space:pre-wrap;">&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:13.5pt;white-space:pre-wrap;">Why Work With Us</strong></b></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="white-space:pre-wrap;">Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><span style="white-space:pre-wrap;">This role will be located in Dublin, IE or Cambridge, UK and is hybrid with a minimum of 3 days per week onsite.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10.25pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p>