INTERNSHIP (WITH POTENTIAL PHD OPPORTUNITY) – ANTIBODY AND PEPTIDE LIBRARY TECHNOLOGIES
InternEntryOthersCancer TherapyAntibodies, PeptidesMasters
Description
We are seeking an experienced and motivated student to join our Biology team. In this role, you will mainly focus on designing, building and screening antibody and peptide libraries to isolate new binders against targets of pharmaceutical interest. In collaboration with other research groups, you will be involved in the design, cloning, production, purification and testing of novel antibody and peptide-based therapeutics using both standard and advanced biomolecular techniques. This project may also foresee collaborations with prominent Universities or partnered Pharmaceutical companies.
**Key Responsibilities:**
- Design and construct diverse antibody and peptide libraries (e.g., Phage display and other display methodologies)
- Develop and optimise selection/screening strategies to identify high-affinity binders
- Characterise hits using biochemical and biophysical assays (e.g., ELISA and SPR)
- Analyse sequencing data to assess library diversity and enrichment
- Collaborate with cross-functional teams for downstream validation and lead optimisation
- Utilize a variety of molecular biology, protein expression, and purification techniques to advance therapeutic prototypes.
Requirements
- Master Degree in Biology, Chemistry, Biotechnology, Pharmaceutical Sciences, or a related field.
- Experience in protein engineering
- Strong knowledge of immunology and antibody-based therapeutics.
- Expertise in molecular biology techniques (e.g., primer design, cloning, PCR, vector design).
- Experience with protein expression and purification (both prokaryotic and eukaryotic systems).
- Proficiency in analytical protein biochemistry (e.g., SDS-PAGE, Size Exclusion Chromatography, flow cytometry, surface plasmon resonance).
- Experience in Solid Phase Peptide Synthesis (SPPS) and analytical skills (HPLC; LC-MS)
- Strong scientific writing and PowerPoint presentation skills.
Philochem
PHARMACEUTICAL
Chemical Pharmaceutical Products, Imaging Markers
LocationSwitzerland - Otelfingen
Open Jobs4
Cancer ImmunotherapyCancer therapy and inflammatory diseasesCancer Therapy
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