Imaging Lead (Sr. Principal Scientist)

Job Description

The Imaging Lead (Sr. Principal Scientist) works with Clinical Imaging Scientists to support clinical trial teams in the use of medical imaging in clinical trials. The Imaging Lead provides leadership on the medical and scientific aspects of the use of imaging and oversees the work of the Clinical Imaging Scientist to ensure that timelines and deliverables are met and of high quality.

The Imaging Lead leads scientific and operational initiatives and oversees the implementation of operational improvements by Clinical Imaging Scientists. This position will work closely with the Head of Clinical Imaging, Imaging Operations Lead and Clinical Imaging Scientists to provide support internally and externally, as follows:

• Provide medical and scientific leadership in the use of clinical imaging in clinical development in broad categories of disease indications, or entire therapeutic areas.

• Interface with internal stakeholders and external collaborators (such as imaging service vendors) to ensure seamless execution and support for the imaging component of clinical trials.

• Design and oversee existing imaging strategies for early and late-stage clinical trial support.

• Exercise foresight and judgment in planning, organizing, and guiding complex imaging projects.

• Work across departments to advance imaging processes, and as needed, challenge the status quo to foster innovation.

• Work with quality and compliance teams for quality-related decision making internally, and assist with vendor audits as needed.

• In regulatory inspections, provide responses to any imaging-related information requests.

• Identify needs and lead internal initiatives and collaborations, with a focus on scientific innovation to advance the application of imaging in clinical development and decision-making.

• Make complex decisions and troubleshoot in ambiguous situations across departments.

• Regularly interact as an imaging subject matter expert with clinical management in early and late-stage clinical trials establishing a track record of successfully applying high level scientific judgement in complex situations

• Develop expertise and leadership in topics and processes that apply to and affect the entire program.

• Support industry presence for our company in clinical imaging at national meetings.

• May provide strategic direction through leadership of up to three direct reports.

Qualifications, Skills & Experience

• Education Minimum Requirement: MD required.

• At least 6 years of experience supporting clinical development in industry is preferred.

• Knowledge of the use of imaging in clinical trials for evaluation of efficacy and safety.

• Skill in authoring and reviewing imaging documents for clinical trials.

• Regulatory experience supporting drug filings.

Required Skills:

Clinical Development, Clinical Medicine, Clinical Trial Development, Clinical Trials, Data Analysis, Imaging Technologies, Medical Imaging, Regulatory Compliance, Scientific Leadership, Scientific Publications, Strategic Leadership

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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The salary range for this role is

$282,200.00 - $444,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Remote

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

05/30/2026

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