HSC Formulation Advisor

<p style="text-align:left">At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.</p><p style="text-align:inherit"></p><div><p><span><span>Come join the rapidly expanding Eli Lilly Gene Therapy Team! We </span><span>are responsible for</span><span> inventing, characterizing, and advancing novel gene therapy reagents for a myriad of clinical applications. Our team works cross-functionally within our organization across multiple disease areas and platforms. Our goal is to deliver </span><span>on the promise of gene</span><span> therapy to patients around the world. This role may require up to 10-15% travel for conferences or training and will include the opportunity to mentor and train two junior scientists. The position is </span><span>located</span><span> at 15 Necco St, Boston MA 02210. Full time (</span><span>40 hours</span><span>/week). To apply, </span><span>submit</span><span> </span><span>resume</span><span> via this site.</span></span><span> </span></p></div><div><p></p><p><b><span>Job </span><span>Responsibilities</span></b><span> </span></p></div><div><ul><li><p><span><span>Formulation and characterization of nanoparticle platforms for nucleic acid delivery (</span><span>e.g.</span><span> Electrophoresis</span><span>, DLS, HPLC, etc.)</span></span><span> </span></p></li></ul></div><div><ul><li><p><i><span>In vitro</span></i><span><span> evaluation of nucleic acid formulation</span><span>, including </span><span>expertise</span><span> on cellular receptors and targeting</span><span> (</span><span>e.g.</span><span> mammalian cell culture, transfection, </span><span>receptor </span><span>density</span><span> and internalization, </span><span>etc</span><span>) </span></span><span> </span></p></li></ul></div><div><ul><li><p><span><span>Act as a SME in the </span><span>HSC targeting</span><span> space</span><span> cross-functionally, and openly communicate with necessary teams</span></span><span> </span></p></li></ul></div><div><ul><li><p><span><span>Development of a</span><span>ctively targeted nanoparticle platform, including target receptor identification/</span><span>selection</span><span> in the context of receptor biology, target </span><span>engagement</span><span> and receptor internalization kinetics; ligand selection/curation; particle decoration and related characterization techniques.</span></span><span> </span></p></li></ul></div><div><ul><li><p><span><span>Perform R&amp;D on novel assay</span><span>s</span><span> to bring in </span><span>new technologies</span><span> to the broader team</span></span><span> </span></p></li></ul></div><div><p></p><p><b><span>Basic Requirements</span></b><span> </span></p></div><div><ul><li><p><span><span>PhD </span><span>with 0-</span><span>3&#43;</span><span> years of related experience</span></span></p></li></ul><p><span><span>OR </span></span></p><ul><li><p><span><span>BS/MS with 5&#43; years of related experience</span></span></p></li></ul><p></p><p><b>Additional Skills &amp; Preferences</b></p></div><div><ul><li><p><span><span>Strong background in HSC biology and formulation, including flow cytometry, qPCR, </span><span>ddPCR and related technologies </span> </span></p></li></ul></div><div><ul><li><p><span><span>Experience with automation</span><span> and NGS</span><span> </span><span>library prep </span><span>is a plus</span></span><span> </span></p></li></ul></div><div><ul><li><p><span><span>Experience with handling NGS data a plus</span></span><span> </span></p></li></ul></div><div><p></p></div><p style="text-align:left">Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (<a target="_blank" href="https://careers.lilly.com/us/en/workplace-accommodation"><span><span><span class="WCO0">https://careers.lilly.com/us/en/workplace-accommodation</span></span></span></a>) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.</p><p style="text-align:inherit"></p><p style="text-align:left">Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.</p><p style="text-align:left"><br />Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ&#43; Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.</p><p style="text-align:inherit"></p><p style="text-align:inherit"></p><p style="text-align:left">Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is</p>$138,000 - $224,400<p style="text-align:inherit"></p><h3></h3><p style="text-align:left">Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.</p><p style="text-align:inherit"></p><p style="text-align:left">#WeAreLilly</p>