Health Economics Manager (Senior Specialist Health Outcomes Research)

Job Description

Calling all health economists!

We are recruiting for a new Health Economics Manager (Senior Specialist), based in Moorgate, London. This is an opportunity to join one of the UK’s largest and most active HTA & Outcomes Research teams and to help secure national access to innovative medicines and vaccines.

The successful candidate will lead and deliver high-quality health economic analyses to support national access to medicines and vaccines, ensuring strong submissions to UK HTA bodies (e.g. NICE, SMC, JCVI) as part of a cross-functional team.

What you will do:

HTA & Value Assessment

• Develop and write economic sections of HTA and vaccine submissions
• Build and validate cost-effectiveness and budget impact models
• Ensure clarity, robustness, and quality of economic evidence
• Manage external vendors producing models or analyses
• Represent the company in HTA meetings and advisory settings
• Contribute to submission strategy and resolve technical challenges
• Cross-functional & Global Collaboration
• Work closely with UK, global, and external stakeholders
• Input into clinical trial design and global model development
• Align with pricing, medical, and market access teams
• Communicate risks, opportunities, and evidence needs

Evidence Generation

• Support studies to address evidence gaps (incl. real-world data)
• Contribute to systematic reviews, NMAs, and methodological research
• Generate economic evidence across a product’s lifecycle

Lifecycle & Strategic Support

• Assess pipeline products for HTA risks and opportunities
• Support launch planning and market access strategy
• Contribute to cross-functional planning and horizon scanning

Capability Building

• Maintain expertise in health economics and HTA methods
• Support team knowledge development and best practice

Key Skills & Focus

• Strong health economic modelling and HTA expertise
• Clear, concise scientific communication
• Stakeholder collaboration (internal & external)
• Strategic thinking across product lifecycle

Qualifications, Skills & Experience Required: 

• Master's degree in Health Economics or related discipline 
• Strong experience in some or all of economic modelling, evidence synthesis, outcomes research, HTA dossier preparation and responding to feedback and clarifications from HTA agencies
• Knowledge of NICE methods and processes
• Understanding of the NHS

 Competencies/Skills:

• Excellent communication skills (verbal and written as well as presentation skills) 
• Quantitative and statistical literacy; comfortable working with complex datasets and assumptions; excellent analytical skills
• Working collaboratively in a matrix organisation
• Strong organisational and prioritisation skills across multiple concurrent projects
• Proven ability to lead end‑to‑end HTA projects to tight timelines and high quality

What we offer:

• The opportunity to be involved in a broad range of therapy areas and a large volume of submission work
• High levels of autonomy and ownership in developing HTA submission dossiers in-house
• Involvement in the end-to-end HTA work, from clinical trial design to post-HTA approval
• Being part of a global organization and collaborate with colleagues around the world
• Have the chance to influence global and local decision making that impacts the lives of thousands of people
• A supportive and positive company culture
• Professional development and training opportunities

Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Closing date: 21st June 2026

Required Skills:

3D Model Making, Clinical Study Design, Clinical Trials, Data Management, Health Economics, Health Outcomes Research, Market Access, Medical Economics, Outcomes Research, Product Lifecycle, Psychotherapy, Researching, Sketch Modelling, Stakeholder Relationship Management, Strategic Planning

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

06/21/2026

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