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<div class="content-intro">About Stoke: Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights STK-002 is Stoke’s proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals. Stoke’s initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company’s proprietary approach.</div>Position Purpose: The Executive Director/Vice President, Field Leader – Market Access Field National &amp; Regional will be responsible for building and leading Stoke’s market access organization, including Market Access Account Directors (MADs) and Field Reimbursement Managers (FRMs). This leader will develop and execute the field strategy to ensure broad, timely, and sustained access to Zorevunersen across payers and ensure provider sites are compliantly supported on reimbursement processes. The role will focus on establishing trusted relationships with national and regional payers, Commercial and Medicaid, along with healthcare providers to minimize barriers to patient access. As part of the Market Access leadership team, this individual will play a critical role in launch readiness and in shaping the access culture for a first-in-class rare-disease therapy. Key Responsibilities: Leadership &amp; Strategy <ul> <li>Build and lead a high-performing market access field access organization, including hiring, developing, and managing MADs and FRMs.</li> <li>Translate corporate access objectives into actionable field plans that align payer, provider, and patient needs.</li> <li>Establish clear goals, metrics, and performance standards for the field team consistent with company objectives and compliance requirements.</li> </ul> Payer &amp; Channel Engagement <ul> <li>Oversee MADs responsible for engagement with national and regional payers, FFS Medicaid, IDNs to secure favorable coverage and reimbursement.</li> <li>Provide strategic guidance for payer value propositions, opportunities, and pull-through initiatives.</li> <li>Collaborate with Market Access Marketing and Distribution to ensure alignment of payer messages and field materials with overall access strategy.</li> </ul> Reimbursement &amp; Patient Access <ul> <li>Lead FRMs in educating providers, infusion sites, and office staff on coverage, reimbursement processes, prior authorization, and patient support programs.</li> <li>Partner with the Patient Services and Specialty Distribution to ensure seamless access and reimbursement support for patients and providers.</li> <li>Ensure FRM field activities are compliant, educational, and aligned with corporate policies.</li> </ul> Cross-Functional Collaboration <ul> <li>Work closely across Commercial, Medical Affairs, and Compliance to ensure consistent and compliant field engagement.</li> <li>Collaborate with Commercial Operations to provide field insights and inform payer strategy, forecasting, and access performance tracking.</li> <li>Partner with Distribution and Patient Services to ensure coordinated communication with external partners impacting patient access.</li> </ul> Compliance &amp; Governance <ul> <li>Ensure all field team activities adhere to company policies, legal requirements, and industry regulations.</li> <li>Collaborate with Compliance to maintain appropriate field training and certification.</li> <li>Support audit readiness and continuous improvement of compliant field operations.&nbsp;</li> </ul> Required Skills &amp; Experience:&nbsp; <ul> <li>12+ years in U.S. market access or reimbursement, including significant field leadership experience.</li> <li>Bachelor’s degree required; advanced degree (MBA, MPH, PharmD) preferred.</li> <li>Proven track record building and leading national payer and reimbursement teams for specialty or rare-disease launches.</li> <li>Deep understanding of payer dynamics, specialty pharmacy networks, buy-and-bill models, and patient access programs.</li> <li>Ability to operate strategically and hands-on in a resource-constrained, rapidly evolving environment.</li> <li>Exceptional leadership and people-development skills.</li> <li>Strong analytical, negotiation, and strategic planning capabilities.</li> <li>Excellent collaboration and communication across internal and external stakeholders.</li> <li>Passion for patient access and rare-disease impact.</li> </ul> Location(s): Stoke is located in Bedford, MA and will be moving to a new location in Waltham, MA by the end of 2026.&nbsp; This position is a field-based position.. Travel: This position will require approximately 50 travel. Compensation &amp; Benefits: At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program. The anticipated salary range for this role at the Executive Director level is $299,000 - $345,000 and at the Vice President level $333,000 - $375,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation. Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).<div class="content-conclusion">Culture &amp; Values: At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation. Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do.&nbsp; Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center: <a href="https://www.stoketherapeutics.com/careers/">https://www.stoketherapeutics.com/careers/</a> For more information, visit https://www.stoketherapeutics.com/. All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status. Stoke participates in E-Verify.</div>

Executive Director/Vice President, Field Leader, Market Access Field National & Regional

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Stoke Therapeutics

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