Evidence Synthesis Manager, HTA

Job purpose:

Reporting to the Evidence Strategy & Operations Lead, this role operates across therapeutic areas to deliver payer‑focused evidence generation, drive HEOR activities for priority assets.  The role has a strong HTA focus and will drive HTA submission projects, prioritising evidence packages and dossier development to meet local HTA and reimbursement requirements; coordinate evidence generation, modelling and stakeholder engagement; and provide HTA‑specific scientific and strategic input to secure favourable access outcomes.

Key Responsibilities:

Evidence synthesis & health economics

• Lead health economics projects to generate high quality and timely data to support the access of prioritised brands to the Japan market, including leading and executing evidence synthesis activities: systematic literature reviews (SLRs), targeted literature reviews (TLRs) and meta-analyses to support HTA, economic models and payer evidence needs.
• Responsible for the development and delivery of Japan health technology assessment (HTA) submissions including development and agreement of strategy, liaison with internal and external senior stakeholders and the reimbursement bodies.
• Input into pricing decisions for brands to ensure that cost effectiveness is appropriately considered in decision making.
• Collaborate with Asset Leads in Japan and Global Real-World Evidence & Health Outcomes Research (RWE-HO), local cross-functional teams, including Government Affairs & Market Access (GAMA), regulatory and development to ensure payer/ value evidence are developed with a full understanding of the requirements of Japan health system/ policy landscape.

Capability building & stakeholder engagement

• Build relationships with HTA bodies, payer advisors, clinical experts, and academic institutions to ensure external relevance and scientific credibility.
• Monitor healthcare policy, HTA trends, and competitive landscape to inform proactive evidence planning.
• Drive discipline in performance reporting and ensure studies are delivered according to plan and within budget.
• Champion the role and value of HEOR internally, increasing understanding across functions on how evidence supports access and adoption.

Desired qualifications & experience:

• Advanced degree (Master’s or PhD) in Health Economics, Public Health, Pharmacy or a related discipline.
• Minimum 3 years of experience in RWE/ HEOR research, or market access in the pharmaceutical, consulting, or healthcare industry in Japan.
• Deep understanding of Japan’s healthcare system, pricing rules, and HTA processes (e.g., C2H framework).
• Demonstrated experience with health economic modelling adaptation, real-world evidence generation, and HTA.
• Proven ability to translate stakeholder insights into strategic evidence generation plans.
• Strong collaboration and communication skills across matrix environments.
• Bilingual proficiency in Japanese (JLPT1 level) and English (verbal and written).
• Experience leading cross-functional initiatives or capability-building projects is preferred

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Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

We are committed to creating an inclusive workplace and providing equal opportunities for all applicants. We embrace an agile working culture across our roles, so if flexibility is important to you please discuss opportunities with our hiring team. If you need any adjustments to the recruitment process to help you demonstrate your strengths and capabilities, contact APACRecruitment.Adjustments@gsk.com. Please note this email is for adjustment requests only; for other enquiries please use our standard contact channels.

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