Domain Architect - Pharma R&D

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The Position

Domain Architect - Pharma R&D

The Domain Architect – Pharma R&D is a senior-level, key position within the Strategy, Portfolio & Governance Enterprise Architecture Business Partnering Functions team. This position plays a critical role between the Strategy, Portfolio & Governance (SPG) organization and the Pharma R&D function. Reporting directly to the Head of Enterprise Architecture Business Partnering Functions with a dotted line to the Global Head of Digital Technology - Pharma R&D, you will champion our enterprise architecture practices while deeply understanding the unique complexities of the Pharma R&D environment.

Crucially, in our federated Roche Digital Technology (RDT) model, you will act as the principal orchestrator of the Pharma R&D architecture network. By leading this network—which includes yourself alongside all domain and solution architects embedded directly within the Pharma R&D organization—you will drive architecture governance and strategy formulation, ensure enterprise coherence, and translate business goals into adaptable, future-ready roadmaps.

Description of the Area

The Enterprise Architecture Business Partnering Functions area serves as the strategic architectural point of contact for business domain leaders, fostering collaboration to align applications, business capabilities, and information assets with technology solutions. For the Pharma R&D domain, this involves deeply integrating with teams such as Clinical Trial Execution & Quality, Patient Safety & Medical Affairs, Biometrics and Clinical Evidence, Regulatory Affairs & China Clinical Development, Discovery & Preclinical and R&D Portfolio Management and Operational Excellence to drive efficiency and innovation with end-to-end accountability. This role ensures that the bridge between SPG’s enterprise vision and Pharma R&D’s operational execution is seamless, collaborative, and highly effective.

The Opportunity:

• You will act as the strategic liaison between SPG EA and Pharma R&D, partnering with leadership to align business priorities with multi-year roadmaps.

• You lead the Pharma R&D architecture network, shaping shared strategic priorities and enabling architects to execute while maintaining enterprise alignment.

• You provide leadership for architecture governance activities, overseeing deliverables and technology guardrails to ensure security and resilience.

• You drive the success of large, critical technology programs by translating strategy into actionable, transformative initiatives that deliver business value.

• You develop and maintain core architecture artifacts, including Capability Maps and Target-State Architectures, using the standard RDT toolchain.

• You partner with Portfolio Management to embed architectural insights into investment decisions, maximizing platform reuse and managing technical debt.

• You monitor emerging technology trends and evaluate vendors to ensure the Pharma R&D architecture remains innovative and future-ready.

• You influence a complex, federated RDT model, balancing enterprise coherence with the agility required for local operational execution.

Who you are:

• You hold a Master’s degree and bring previous experience in IT and enterprise architecture, specifically within complex, matrixed, or federated global organizations.

• You possess deep domain experience in Pharma R&D, with a comprehensive understanding of scientific and clinical processes (e.g., Clinical Trial Execution, Discovery & Preclinical, Biometrics, and Regulatory Affairs).

• You are a visionary architect capable of designing target-state architectures and capability roadmaps that evolve alongside business needs, utilizing frameworks like TOGAF as a reference for trade-off analysis rather than a rigid set of rules.

• You navigate regulatory landscapes with ease, balancing compliance with agility in environments governed by GxP, 21 CFR Part 11, and other industry-standard regulations.

• You drive the future of AI in Life Sciences, with a sophisticated understanding of AI/ML platform orchestration and emerging agentic patterns (MCP, A2A) to automate and enhance scientific workflows accounting for a human-in-the-loop design.

• You are a master of application portfolio strategy, skilled at mapping dependencies and sequencing the decommissioning of legacy systems to ensure business continuity during digital transformations.

• You excel at governing through influence, leading federated networks of architects and inspiring diverse partners to align with a unified voice without the need for direct reporting lines.

• You are a trusted advisor to senior leadership, combining executive presence with storytelling to translate complex architectural concepts into strategic narratives that guide high-level decision-making.

What you get:

• Salary range 23 300 - 43 300 PLN gross based on the employment contract.

• Annual bonus payment based on your performance.

• Dedicated training budget (training, certifications, conferences, diversified career paths etc.).

• Recharge Fridays (2 Fridays off per quarter available).

• Take time Program (up to 3 months of leave to use for any purpose).

• Vacation subsidy available.

• Flex Location (possibility to perform our work from different places in the world for a certain period of time).

• Take Time for Charity (additional paid leave of maximum 2 weeks to engage in the charity action of your choice).

• Private healthcare (LuxMed packages), group life insurance (UNUM) and Multisport.

• Stock share purchase additions.

• Yearly sales of company laptops and cars and many more!

Apply directly and join us in shaping the future of healthcare.

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Compensation & Benefits

This position also offers an attractive benefits package.

Learn more about how we reward our employees at Roche.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.