Director / Senior Director, Discovery & Investigative Toxicology (Multispecific Antibodies)

We are seeking a Director or Senior Director of Discovery & Investigative Toxicology to provide scientific leadership in early safety assessment, in vitro screening, and mechanism-based toxicology for our bispecific/multispecific antibody discovery portfolio. This role is intentionally focused on investigative toxicology and early risk mitigation, with particular emphasis on liabilities unique to bispecific/multispecific antibody modalities, including exaggerated pharmacology, target cross-linking, avidity-driven biology, tissue sink effects, and complex PK–tox relationships. The successful candidate will partner closely with Discovery Biology, Protein Engineering, and Pharmacology to design and apply in vitro and in vivo strategies that identify and mitigate safety risks early, before programs transition into formal development. Experience with later-stage project toxicology and GLP toxicology assessments is considered a strong plus but is not required, and will be valued primarily for the ability to translate discovery-stage insights into development-ready strategies. The ideal candidate is a biology-first toxicologist who combines deep mechanistic understanding with practical experimental judgment to de-risk complex antibody formats at the discovery stage.