Director, Molecular Pathology, Translational Sciences, Translational Research.

The Opportunity:

As a Director, Molecular Pathology, you will be a key member of a cross-functional Translational Sciences Team, reporting to the Senior Director and Head of Translational Sciences within Translational Research and will:

• Biomarker Strategy: Define and execute molecular and digital pathology-driven biomarker strategies.

• Integration of Advanced Modalities: Lead adoption of molecular pathology and spatial technologies (to support translational research and broader BDR needs.

• Digital & Computational Pathology: Drive implementation of whole-slide imaging, AI/ML-based image analysis, and integration of spatial biomarker analytics into decision-making.

• Data Interpretation & Reporting: Provide expert interpretation of pathology data, ensuring robust correlation with clinical outcomes and mechanistic insights.

• Cross-functional Leadership: Collaborate with Translational Medicine, Bioinformatics, and Clinical Development colleagues to implement candidate biomarkers into Translational Biomarker plans for RAS(ON) inhibitors in alignment with overarching clinical development strategies.

Responsibilities

• Scientific Leadership & Execution: Perform and interpret multiplex spatial biomarker datasets to inform Translational hypotheses and clinical strategies. Establish QC standards for data acquisition and analysis.

• Cross-Functional Collaboration: Partner within Research and Clinical teams to integrate spatial biomarker findings into translational plans. Collaborate with Systems Biology and Information Sciences teams to enable visualization tools

• External Partnership Management: Serve as primary scientific liaison to CROs for spatial biomarker workflows; review deliverables, troubleshoot issues, and drive continuous improvement.

• Capability Building: Document best practices and SOPs for spatial biomarker workflows; recommend platform upgrades and pilot evaluations.

Required Skills, Experience & Education:

• 10+ years in digital pathology/spatial biology within pharma, biotech, or CRO settings.

• Scientific Expertise: Deep knowledge of spatial biology (e.g. spatial transcriptomics, Visium, Xenium, GeoMx, MerFish, etc.); ability to translate complex data into actionable insights

• Execution Excellence: Bias for action; delivers high-quality analyses under tight timelines

• Collaboration & Influence: Builds strong relationships across functions and with external partners; communicates clearly and persuasively.

• Innovation & Continuous Improvement: Identifies opportunities to enhance workflows and adopt emerging technologies.

• PhD/MD or equivalent in Cancer Biology, Translational Sciences, Pathology or related discipline.

Preferred Skills:

• Hands-on experience with spatial pathology workloads.

• Familiarity with AI/ML-assisted pathology workflows and spatial statistics.

• Proven ability to manage CRO relationships and deliver time-sensitive biomarker analyses.

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