Director, In Vivo Research

<p>At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as <i>Science</i> magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on <i>The Sunday Times</i> Best Places to Work list in the UK.</p><p></p><p>For patients, for each other, and for the future of science, we’re in. Are you?</p><p></p><p style="text-align:inherit"></p><p style="text-align:left"><b>About the Role:</b></p>We’re looking for an exceptionally self-motivated, intellectually curious, and entrepreneurially minded Director, In Vivo Research with deep expertise in translational research for Insmed’s New Jersey Research Team to help us expand what’s possible for patients with serious and rare diseases. <br><br>Reporting to the Senior Director of Research, you will lead rodent disease model development and the design and execution of preclinical in vivo studies and will collaborate closely with peers across the research organization to drive Insmed’s pipeline programs from discovery towards IND.<p style="text-align:inherit"></p><p style="text-align:left"><b>What You&#39;ll Do: </b></p><p>In this role, you’ll provide strategic leadership for the in vivo pharmacology function to enable Insmed’s early-stage research pipeline and advance innovative therapies to the clinic.</p><p></p><p>You’ll also:</p><ul><li><p>Identify, validate, and implement appropriate PK/PD models to support candidate selection</p></li><li><p>Develop and execute in vivo pharmacology strategies for efficacy, PK/PD, biodistribution, and safety evaluations in rodents</p></li><li><p>Contribute to the strategic vision for PK/PD and in vivo pharmacology to support portfolio and candidate selection decisions across early research programs</p></li><li><p>Lead, develop, and build a team of in vivo scientists</p></li><li><p>Partner closely with cross-functional teams to support in vivo pharmacology needs and integrate with toxicology and translational strategies</p></li><li><p>Review, interpret, and communicate complex data to internal stakeholders and senior leadership</p></li><li><p>Author and review protocols, electronic notebook entries, technical reports, and scientific publications</p></li><li><p><span>Provide oversight and scientific input for pharmacology studies conducted by CROs and academic partners</span></p></li><li><p><span>Contribute to external scientific presence, including authorship and review of publications, abstracts, and presentations, as appropriate</span></p></li><li><p>Ensure compliance and best practice related to IACUC protocols and all relevant regulatory and ethical standards for animal research</p></li></ul><p style="text-align:inherit"></p><p style="text-align:left"><b>Who You Are:</b></p><ul><li><p>Ph.D. degree in Life sciences discipline with deep in vivo pharmacology background and 10&#43; years of industry experience, including leadership responsibility</p></li><li><p>Demonstrated success leading in vivo pharmacology strategy for both small molecule entities and biologics</p></li><li><p>Extensive experience proposing, developing, establishing, and evaluating fit-for-purpose in vivo models including but not limited to genetically modified mouse strains and disease models in the immunology, respiratory, and CNS space</p></li><li><p>Strong understanding of PK/PD principles and translational considerations that inform candidate selection and program progression</p></li><li><p>Expert hands-on knowledge in standard dosing and fluid collection techniques and conducting survival surgery in rodents</p></li><li><p>Strong familiarity with IACUC protocols and compliance with ethical and regulatory standards for animal research</p></li><li><p>Demonstrated experience managing projects and leading teams in the context of multiple competing priorities and tight deadlines</p></li><li><p>Experience collaborating and communicating effectively to optimally support functional and cross-functional operations</p></li><li><p>Strategic thinker with an entrepreneurial mindset, proactive problem-solving attitude and strong willingness to take on new challenges</p></li><li><p>High level of organization with a strong attention to detail, clarity, accuracy and conciseness</p></li><li><p>Thrives in a dynamic, fast-paced research environment and is comfortable making decisions with evolving data</p></li></ul><p></p><p><b>Nice to have (but not required):</b></p><ul><li>Hands-on expertise in CNS/brain delivery</li></ul><p></p><p><b>Where You’ll Work </b></p><p>This role is based out of our Bridgewater location and requires full-time, in-person presence to support hands-on collaboration, access specialized equipment, and/or operational needs.</p><p></p><p><b>Travel Requirements</b></p><p>Minimal travel expected</p><p></p><p style="text-align:inherit"></p><p style="text-align:left"><b>Pay Range:</b></p>$185,000.00-252,500.00 Annual<p></p><p><span style="color:#000000"><b>Life at Insmed</b><br /> </span></p><p>At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.</p><p></p><p>Highlights of our U.S. offerings include:</p><ul><li><p>Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)</p></li><li><p>Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration</p></li><li><p>401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance</p></li><li><p>Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities</p></li><li><p>Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back</p></li></ul><p></p><p></p><p>Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. </p><p></p><p></p><p></p><p><i><b>Current Insmed Employees: Please apply via the Jobs Hub in Workday.</b></i></p><p></p><p></p><h3></h3><p></p><p><i>Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.</i></p><p></p><p><i>It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.<br /><br />Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.<br /><br />Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application   or interview process, please contact us by email at </i><a target="_blank" href="mailto:TotalRewards&#64;insmed.com"><span style="color:#0000ff"><i><u>TotalRewards&#64;insmed.com</u></i></span></a><i>  and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.<br /><br />Applications are accepted for 5 calendar days from the date posted or until the position is filled.</i></p><p></p><p><i><b>For New York City Residents:</b></i></p><p><i>To assist in identifying candidates with qualifications matching those required and/or preferred for this role, Insmed uses an Automated Employment Decision Tool (“AEDT”) that employs artificial intelligence to analyze and score information provided in resumes and application materials including, but not limited to, skills, work experience, education, and job-related qualifications. The AEDT does not make final hiring decisions and all final hiring decisions are subject to human oversight and/or review.</i></p><p><br /><i>If you are an applicant for this role and a New York City resident, you have the right to request:</i></p><p> </p><ul><li><p><i>A reasonable accommodation, if one is available under applicable law, by emailing </i><a target="_blank" href="mailto:TotalRewards&#64;insmed.com"><span style="color:#1e53a3"><i><u>TotalRewards&#64;insmed.com</u></i></span></a><i>; and/or</i></p></li><li><p><i>An alternative selection process by emailing </i><a target="_blank" href="mailto:Privacy&#64;insmed.com"><span style="color:#1e53a3"><i><u>Privacy&#64;insmed.com</u></i></span></a><i>.</i></p></li><li><p><i>Information about the type of data collected, the source of that data, and data retention practices related to the AEDT by emailing us at </i><a target="_blank" href="mailto:Privacy&#64;insmed.com"><i>Privacy&#64;insmed.com</i></a><i>.</i></p></li></ul>