Director, Cheminformatics and Predictive Modeling

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Key responsibilities include developing and deploying machine learning models, integrating ML with molecular modeling, collaborating on AI/ML strategies, and advancing computational discovery. The skills required include a PhD or equivalent experience, 8+ years in biotech or pharma, deep experience with ML methods, and a strong understanding of chemical representations and ADME/Tox principles.