Director, Business Strategy & Operations - Commercialization

<div class="content-intro"><h3>Company Overview:</h3> <p>Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at <a href="https://www.dyne-tx.com/">https://www.dyne-tx.com/</a>, and follow us on <a href="https://x.com/dyne_tx">X</a>, <a href="https://www.linkedin.com/company/dynetx/">LinkedIn</a> and <a href="https://www.facebook.com/DyneTherapeutic/">Facebook</a>.</p></div><p><strong>Role Summary:</strong></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body" data-ccp-parastyle-defn="{"ObjectId":"b669530d-9cee-5fd4-8da3-4cdbed7bfaa2|1","ClassId":1073872969,"Properties":[469775450,"Body",201340122,"2",134233614,"true",469778129,"Body",335572020,"1",469777841,"Helvetica",469777842,"Helvetica",469777843,"Helvetica",469777844,"Helvetica",469769226,"Helvetica",335551500,"0",268442635,"22"]}">As Dyne advances toward commercial launch across multiple therapy areas, we are seeking an experienced Business Strategy and Operations leader to play </span><span data-ccp-parastyle="Body">a central role</span><span data-ccp-parastyle="Body"> in shaping and executing our transition from late-stage development to a fully integrated commercial company.</span></span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335551550":1,"335551620":1,"335559685":0,"335559737":0,"335559740":259,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"nil","469789802":"nil","469789806":"nil","469789810":"nil","469789814":"nil"}"> </span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body">The </span><span data-ccp-parastyle="Body">Director, </span><span data-ccp-parastyle="Body">Business Strategy & Operations</span><span data-ccp-parastyle="Body"> -</span><span data-ccp-parastyle="Body"> Commercialization</span><span data-ccp-parastyle="Body"> will play a critical role in enabling the Commercial organization to </span><span data-ccp-parastyle="Body">operate</span><span data-ccp-parastyle="Body"> with clarity, alignment, and executional excellence as Dyne advances toward launch. Acting as a senior strategic and operational partner to the Chief Commercial Officer, this leader ensures that commercial priorities are translated into well‑defined, coordinated, and measurable action across the organization.</span></span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body">This role sits at a key intersection of strategy, operations, and cross‑functional leadership</span><span data-ccp-parastyle="Body">,</span></span> <span data-contrast="none"><span data-ccp-parastyle="Body">ensuring that commercial perspectives, priorities, and readiness are clearly embedded in key priority projects and initiatives. The role provides strong operational leadership and continuity to </span><span data-ccp-parastyle="Body">establish</span><span data-ccp-parastyle="Body"> a world class CCO team, helping translate commercial strategy into coordinated action across the organization.</span><span data-ccp-parastyle="Body"> The Director will help </span><span data-ccp-parastyle="Body">establish</span><span data-ccp-parastyle="Body"> the systems, processes, and operating rhythm needed to dri</span><span data-ccp-parastyle="Body">ve commercial readiness, support the CCO and Commercial Leadership Team, and ensure the organization </span><span data-ccp-parastyle="Body">remains</span><span data-ccp-parastyle="Body"> focused on the highest‑value priorities. They will </span><span data-ccp-parastyle="Body">anticipate</span><span data-ccp-parastyle="Body"> needs, connect workstreams, and bring structure and consistency to a rapidly evolving environment.</span></span><span data-ccp-props="{"134233117":true,"134233118":true}"> </span></p> <p data-ccp-border-bottom="0px none #000000" data-ccp-padding-bottom="0px" data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none"><span data-ccp-parastyle="Body">The ideal candidate brings significant biotech experience, strong strategic and analytical capabilities, and excellent judgment. They are comfortable navigating ambiguity, influencing without authority, and simplifying complexity for senior audiences. This is a high‑impact role with broad visibility across the enterprise, suited for a leader who thrives in a fast‑paced, high‑growth setting and is energized by building and enabling high‑performing teams.</span></span><span data-ccp-props="{"134233117":true,"134233118":true}"> </span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="none">This is a full-time position based in Waltham, MA.</span><span data-ccp-props="{"134233117":true,"134233118":true}"> </span></p> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"> <br><strong><span data-contrast="none">Primary Responsibilities Include:</span></strong><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></p> <ul> <li><span data-contrast="auto">Partner closely with the CCO to translate commercial strategy and priorities into actionable and measurable plans, ensuring clarity, structure, and consistency across initiatives. </span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Establish and manage the operating rhythm for the Commercial organization, including leadership forums, governance processes, decision-focused meetings, and business reviews that drive alignment and follow-through.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Lead and coordinate high‑priority, cross‑functional initiatives essential to commercial readiness, serving as the central connector between Commercial and partner functions with clear roles, responsibilities, and timelines.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Develop and deliver high‑quality executive materials, including Board updates, enterprise presentations, town hall content, and cross-functional communications in partnership with Corporate Affairs.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Support preparation and coordination for the CCO’s engagement with key external stakeholders, such as KOLs, HCPs, patient advocacy groups, strategic partners, and internal senior leaders.</span><span data-contrast="auto"> Ensure interactions are well-prepared, coordinated, and grounded in a clear understanding of priorities and context. </span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Drive operational excellence through OKRs (objectives and key results for the CCO team), dashboards, performance tracking, and business review processes, providing transparency on progress, dependencies, risks, and resource needs.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Promote alignment, communication, and collaboration across Commercial and partner functions to ensure connectivity between strategy and execution.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Help strengthen Commercial team culture by reinforcing collaboration, accountability, and clear communication as the organization grows and prepares for launch.</span><span data-ccp-props="{"134233117":true,"134233118":true,"335557856":16777215,"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> </ul> <p><em><span data-contrast="none"><span data-ccp-parastyle="Body">Leadership Characteristics</span></span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335551550":1,"335551620":1,"335559685":0,"335559737":0,"335559738":0,"335559739":120,"335559740":259,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"nil","469789802":"nil","469789806":"nil","469789810":"nil","469789814":"nil"}"> </span></em></p> <ul> <li data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><span data-contrast="auto">Personal leadership characteristics will be critical to succeed in this role. The successful individual will be highly self-directed, with the judgment, energy, diligence and resilience required to operate effectively in a high-growth, fast-paced biotechnology environment. They will bring a calm, confident leadership presence, strong communication skills, well-articulated, and the ability to influence and align stakeholders across the organization without formal authority.</span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335551550":1,"335551620":1,"335557856":16777215,"335559737":0,"335559740":259,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Consistent with Dyne Therapeutics’ values and patient-centered culture, the individual must demonstrate a genuine commitment to listening to, learning from, and acting in the best interests of the patient communities and shareholders Dyne serves. </span><span data-ccp-props="{"134233117":true,"134233118":true,"201341983":0,"335551550":1,"335551620":1,"335557856":16777215,"335559737":0,"335559740":259,"335572071":0,"335572072":0,"335572073":0,"335572075":0,"335572076":0,"335572077":0,"335572079":0,"335572080":0,"335572081":0,"335572083":0,"335572084":0,"335572085":0,"335572087":0,"335572088":0,"335572089":0,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">A natural alignment with Dyne Therapeutics’ values, including accountability, collaboration, and a deep respect for the needs and experiences of patients and their families.</span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":257}"> </span></li> <li><span data-contrast="auto">The maturity and discretion required to handle sensitive information and complex organizational dynamics.</span><span data-ccp-props="{"134233117":false,"134233118":false,"201341983":0,"335559737":0,"335559738":0,"335559739":0,"335559740":257}"> </span></li> </ul> <p data-ccp-border-between="0px none #000000" data-ccp-padding-between="0px"><strong><span data-contrast="none"><span data-ccp-parastyle="Body">Education</span><span data-ccp-parastyle="Body">, Experience, </span><span data-ccp-parastyle="Body">and Skills Requirements:</span></span></strong><span data-ccp-props="{"335559739":120}"> </span></p> <ul> <li><span data-contrast="auto">10+ years of progressive experience in biotechnology or pharmaceuticals.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Bachelor’s degree required; advanced degree (MBA, PharmD, PhD) preferred.</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Experience supporting at least two successful rare disease product launches in a commercial, strategic, or operational leadership capacity.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Strong cross-functional leadership experience in high-growth, dynamic environments.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Exceptional communication, organization, and influencing skills; able to simplify complex topics for senior audiences.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Highly self-directed and effective in ambiguity; strong judgment, prioritization, and follow-through.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Demonstrated ability to handle confidential information with discretion and build trusted relationships at all levels.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Thrives in dynamic, stretching environments with evolving needs.</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> <li><span data-contrast="auto">Ability to travel as needed; up to 25%</span><span data-ccp-props="{"335572071":0,"335572072":0,"335572073":4278190080,"335572075":0,"335572076":0,"335572077":4278190080,"335572079":0,"335572080":0,"335572081":4278190080,"335572083":0,"335572084":0,"335572085":4278190080,"335572087":0,"335572088":0,"335572089":4278190080,"469789798":"none","469789802":"none","469789806":"none","469789810":"none","469789814":"none"}"> </span></li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="title">MA Pay Range</div><div class="pay-range"><span>$188,000</span><span class="divider">—</span><span>$230,000 USD</span></div></div></div><div class="content-conclusion"><p> </p> <p>The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.</p> <p>The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.</p> <p class="Body"><em><span style="font-family: 'Arial',sans-serif; color: #626262;">Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.</span></em></p></div>