Clinical Site Liaison

Clinical Site Liaison

About the Role

The Clinical Site Liaison (CSL) serves as a key field‑based extension of the Clinical Operations team, responsible for building strong relationships with investigative sites and ensuring high‑quality study execution. This role provides proactive support to sites, facilitates communication between site staff and internal teams, and helps remove operational barriers that impact enrollment, data quality, and patient experience. The ideal candidate thrives in a fast‑moving biotech environment and enjoys being the “face of the study” for clinical sites.

Key Responsibilities

Site Relationship Management

• Serve as the primary point of contact for assigned clinical trial sites, fostering strong, collaborative relationships.
• Conduct regular check‑ins (virtual or on‑site) to assess site needs, enrollment progress, and operational challenges.
• Ensure sites have timely access to study materials, training, and updates.

Enrollment & Study Support

• Monitor enrollment performance and partner with sites to identify recruitment opportunities and barriers.
• Support site‑level feasibility, start‑up activities, and readiness assessments.
• Provide guidance on protocol requirements, visit schedules, and operational expectations.

Quality & Compliance

• Reinforce adherence to protocol, GCP, and study‑specific procedures.
• Identify and escalate potential quality issues, data inconsistencies, or protocol deviations.
• Collaborate with CRAs, Clinical Operations, and Medical Monitoring to ensure timely issue resolution.

Cross‑Functional Collaboration

• Act as a conduit between sites and internal teams (Clinical Ops, Medical Affairs, Data Management, Safety).
• Share site insights to inform study planning, risk mitigation, and operational decision‑making.
• Support vendor coordination (central labs, imaging, ePRO, etc.) as needed.

Operational Excellence

• Participate in investigator meetings, site trainings, and study team calls.
• Contribute to development of site‑facing tools, communications, and best practices.
• Maintain accurate documentation of site interactions and follow‑up actions.

Qualifications

• Bachelor’s degree in life sciences or related field; advanced degree a plus.
• AD Level 8 years, Sr Manager 6 years of experience in clinical research (Clinical Study Manager, CRM or CSL or Clinical Trial Lead).
• Strong understanding of clinical trial operations, GCP, and site workflows.
• Excellent communication, relationship‑building, and problem‑solving skills.
• Ability to travel to investigative sites as needed.  Approximate travel 85%
• Experience in small biotech or fast‑paced clinical environments preferred.

What Success Looks Like

• Strong, trusted relationships with site staff.
• Improved enrollment performance and reduced operational friction.
• High‑quality data and fewer site‑level issues.
• Clear, timely communication between sites and internal teams.
• A positive, supportive site experience that reflects well on the sponsor.

 

 The salary range for the Senior Manager, Clinical Site Liaison is expected to be between $175,000 and $190,000 per year.  Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.

The salary range for the Associate Director, Clinical Site Liaison is expected to be between $195,000 and $210,000 per year.  Individual pay may vary based on multiple factors including but not limited to relevant job-related skills, experience, education or training, market factors, and work location.