Clinical Biomarker Lead- Oncology Translational Medicine

’For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to [Cambridge, UK] . The location of this role will therefore subsequently change to [Cambridge, UK] in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029

Business Introduction

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.

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Our approach to R&D


Position Summary

Are you interested in the development and effective implementation of biomarker strategy to support clinical development across GSK portfolio? Are you searching for a position where you will be working as a key contributor leading development of novel biomarkers for clinical trials and/or as a biomarker lead on clinical matrix team (CMT) and leading development and integration of biomarker strategy into clinical development plans? If so, the Assoc. Director Biomarkers in OTM could be an ideal opportunity to explore.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Work with key external industry and/or academic partners to evaluate, validate and establish key biomarker capabilities and/or generate key biomarker data to support biomarker strategies for clinical trial implementation at GSK. You will be responsible for designing, implementing and managing collaborative projects that aid in developing biomarker capabilities that are of strategic importance to OTM and in alignment with GSK clinical trials.

• Identify, develop and implement cutting edge advances in science and technology into biomarker strategies to guide indication selection, patient enrichment, and combination strategies.

• Provide input to clinical biomarker teams on novel technologies that will enable clinical development of GSK candidate drugs.

• Manage effective working relationships with clinical biomarker leads, medical affairs, oncology tumor teams, portfolio management, competitive intelligence, clinical development and OTM management.

• Coordinate and manage biomarker projects with cross-functional internal stakeholders and external partners

• Contribute to and ensure the quality of OTM biomarker reports, summaries, data reviews and interpretations as applicable. Present key data/findings/accomplishments at internal as well as external scientific forums, lead the preparation and publication of scientific manuscripts as needed.

Why You?


Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

• Ph.D. or equivalent with 3+ years or M.Sc with 7+ years of drug development experience in pharmaceutical industry preferably in oncology biomarker development.

• Experience with biomarker assays, technologies, platforms and providers.

• Experience of implementation of a range of biomarker platforms including flow cytometry, molecular diagnostics (NGS, FISH, PCR), and/or IHC/IF for Oncology clinical trials.

• Experience designing and executing translational biomarker strategies in oncology clinical trials, including assay development, validation, sample testing plans and clinical deployment.

• Experience conducting biomarker analyses on various clinical sample types and delivering biomarker data packages at pace to inform clinical development and regulatory strategies working collaboratively as part of cross-functional matrix teams.

• Experience coordinating and managing key deliverables, timelines, contracts and budgets with internal and external partners.

• Experience working to GCP/GLP principles

• Experience managing multiple priorities and delivering projects within established timelines in a fast-paced environment.

Preferred Qualification

If you have the following characteristics, it would be a plus:

• Strong interpersonal skills and ability to thrive in a matrix environment

• Dependable and trustworthy, willing to take ownership and responsibility

• Experience with high-dimensional dataset analysis.

• Strong communication, organizational, matrix project-management, and presentation skills.

• Experience with digital pathology, AI/ML-enabled biomarker analyses, and external scientific partnerships.

#GSK-LI

Skills

Agile Thinking, Clinical Development, Clinical Trial Designs, Decision Making, Fostering Collaboration, Influencing Without Authority, Leadership, Matrix Leadership, Mentorship, People Management, Project Management, Risk Management, Strategic Thinking, Teamwork, Time Management

 

 

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $150,975 to $251,625. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at - usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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