Biotechnologist (NIGHTS, All Experience Levels)

Biotechnologist (NIGHTS, All Experience Levels) – Cell Therapy & Mammalian Manufacturing 

Shift differentials are available for Night and weekend hours worked.

Location: Portsmouth, NH, USA. The actual location of this job is in Portsmouth, NH, USA.

At Lonza Portsmouth, you won’t just make medicine — you will help shape the future of how it is made. Our site is uniquely positioned at the intersection of personalized Cell Therapy and large-scale Mammalian biologics manufacturing. In one facility, we produce both patient-specific, life-saving cell therapies and high-volume biologic medicines used by people around the world. That means your career here doesn’t live in a single box — it grows across platforms, technologies, and modalities. 

What You’ll Get 

• Meaningful Patient Impact: From individualized therapies made from patient-donated cells to large-scale biologics produced in 2,000L, 6,000L, & 20,000L bioreactors, everything you do directly supports our purpose. 

• Cross-Platform Career Growth: As Lonza expands both Cell Therapy and Mammalian manufacturing, you’ll have opportunities to grow across modalities, technical depth, and leadership tracks. 

• World-Class Training: Develop expertise in Grade B aseptic gowning, cell therapy processing, and large-scale mammalian systems (Upstream & Downstream). 

• Comprehensive Benefits: Medical, dental, vision, 401(k), and global Lonza benefits: https://www.lonza.com/careers/benefits. 

What You’ll Do 

Your responsibilities will scale with your experience and may span both Cell Therapy and Mammalian Manufacturing depending on business needs and your career path. 

Cell Therapy Focus 

• Work in Grade B cleanrooms requiring full sterile gowning. 

• Perform aseptic processing inside laminar flow hoods using strict sterile technique. 

• Receive, process, expand, and cryopreserve patient-derived primary cells. 

• Execute flawless cGMP documentation for individualized patient batches. 

Mammalian Manufacturing Focus 

• Operate mammalian cell culture bioreactors (2,000, 6,000, and 20,000). 

• Execute both upstream and downstream processes.  

• Set up, operate equipment, and monitor production processes, including clean-in-place (CIP) and steam-in-place (SIP) operations and report production in written and electronic documents in accordance with good manufacturing practice (GMPs) and good documentation procedures (GDPs). 

• Conduct in-process testing pH, conductivity, metabolites, etc. 

Who We’re Looking For 

We hire across all experience levels and build teams that grow together. 

• Foundational / Early-Career: No prior biotech experience required. We look for high attention to detail, reliability, and an interest in learning a highly specialized life-science trade. 

• Intermediate (Level II / III): 1–5 years of experience in regulated manufacturing or clinical labs. Experience with aseptic technique, cleanrooms, or bioreactors is a plus. 

• Advanced / Senior: 5+ years of GMP experience. Track record of leading complex operations, mentoring others, and owning deviations. 

• Education: High School Diploma required for all levels; Associate’s or Bachelor’s in STEM preferred for intermediate and advanced roles. 

• Schedule: Ability to work a rotating 12-hour shift (Night 7 PM – 7 AM). Our rotation follows a predictable pattern: Work 2 days on, 2 off, 3 on, 2 off, 2 on, 3 off. This ensures consistent time off and includes every other weekend. 

Why Lonza Portsmouth 

Lonza is one of the world’s largest and most trusted CDMOs, with 30+ sites across five continents. Portsmouth is special—it’s one of the few places in the industry where cutting-edge cell therapy and large-scale biologics live side-by-side. Here, you don’t just fill a role—you build a career platform that can take you anywhere in biopharma. 

Ready to help manufacture the future of medicine? Apply now.