Associate Scientist in Analytical Development for Synthetic Molecules

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The Position

 Behind each product in clinical trials or sold by Roche is the involvement of Pharma Global Technical Operations. Pharma Global Technical Operations makes medicines with more than 10’000 employees at sites around the world. “Pharma Technical Development” is a global organization with over two thousand people dedicated to the development of new medicines to meet patients' needs. We actively collaborate and develop creative technical solutions to expertly deliver the pipeline and supply high quality products to patients. The group excels in its work through innovation, teamwork, dedication, and mutual respect and contributes every single day to bring new therapies to life and hope to patients.

“Synthetic Molecules Technical Development” (PTDC) brings a broad range of experience across drug substance, drug product, and analytical sciences, and collaborates closely with partners in research and early development, Pharma Technical Development, and commercial. PTDC is responsible for the technical development of our synthetic molecules pipeline and the manufacture of clinical supplies for clinical studies. The position on offer is located in analytical development for synthetic molecules within Pharma Technical Development.

Analytical development for synthetic molecules is responsible for the development of resource and cost efficient analytical methods by use of state of the art and innovative techniques such as high-performance liquid chromatography, gas or ion chromatography or mass spectrometry. The ultimate goal of our work is the development of a robust control strategy to release products for clinical trials, and finally for commercial supply.

The opportunity

The (Senior) Associate in Analytical Development for Synthetic Molecules is responsible for:

• Performing routine measurements for Oligonucleotides (mainly HPLC with UV and/or Single Quad MS detection)

• Use chromatographic data systems like Empower or OpenLab to control analytical instruments. Evaluate data with Genedata or Oligo Analysis Accelerator

• Thorough and efficient planning, execution and documentation of experiments in collaboration with the relevant team members, analytical project lead and your supervisor, following current GxP guidelines as well as the relevant SOP’s.

• Developing, improving, and validating analytical methods for the quality assessment of Oligonucleotides.

• Evaluation of new technologies/methods and support of innovation projects.

• Authoring of documents, e.g. analytical procedures, and validation reports.

Who you are

For this interesting challenge, you bring the following qualification:

You have completed vocational scientific qualification (e.g. apprenticeship, Laborant EFZ or equivalent) with at least 1-3 years’ experience in the pharmaceutical industry with a strong focus on analytical methods development (i.e. chromatography). Further qualification (e.g. HFP, BSc) is a plus. This position is primarily focusing on lab work. Applications of MSc or PhD will not be considered.

• Hands-on experience in analytical instrumentation and techniques (e.g. HPLC, GC, KF)

• Experience with LC/MS measurements for oligonucleotides or peptides would be a plus. However, we encourage candidates who want to develop and learn these exciting techniques. 

• A strong interest / background in analytical methods development

• A good scientific writing style and good documentation practice

• Excellent digital skills and innovative mindset

• Preparedness to learn, continuously improve and apply novel ideas, tools and processes to quickly adapt to a fast changing environment.

• Excellent command of English. Good command of German would be a plus.

• Routinely apply GxP requirements where necessary, and understand how to exert them in different clinical phases. 

Apply now -  we look forward to hearing from you!

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.