Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
Position Summary
The Associate Director, Strategic Sourcing will lead strategic sourcing initiatives and category management activities supporting Chemistry, Manufacturing & Controls (CMC), Supply Chain, and Quality Assurance (QA) functions. This role is responsible for developing and executing sourcing strategies, managing supplier relationships, negotiating contracts, driving value creation, mitigating supply risk, and ensuring alignment with business objectives in a dynamic and highly regulated biopharmaceutical environment.
The successful candidate will partner closely with Technical Operations, Manufacturing, Quality, Regulatory, Supply Chain, Finance, Legal, and other stakeholders to support clinical and commercial programs while ensuring continuity of supply, quality compliance, and cost optimization.
Key Responsibilities
Strategic Sourcing & Category Management
- Develop and execute category strategies for CMC, Supply Chain, and Quality-related spend categories, including but not limited to:
- Contract Development and Manufacturing Organizations (CDMOs)
- Support analytical and CMC activities
- Raw materials, APIs, excipients, and packaging components
- Logistics, transportation and warehousing services
- Quality and compliance consulting services
- Conduct market assessments, supplier evaluations, and benchmarking to identify opportunities for cost savings, innovation, risk mitigation, and operational efficiency.
- Lead competitive sourcing events including RFIs, RFPs, RFQs, supplier selection, and contract negotiations.
Supplier Relationship Management
- Build and maintain strategic relationships with key suppliers and service providers.
- Establish supplier performance metrics and governance frameworks to monitor quality, delivery, service, innovation, and compliance.
- Facilitate regular business reviews with critical suppliers.
- Help define and track KPIs that measure sourcing and procurement performance, supplier reliability, regulatory/SOP adherence, and value creation across scientific and non-scientific categories.
- Collaborate with business stakeholders to resolve supplier performance issues and drive continuous improvement initiatives.
Contracting & Negotiations
- Lead complex commercial negotiations, including Master Service Agreements, Quality Agreements, Supply Agreements, Statements of Work, and pricing arrangements.
- Partner with Legal, Quality, Finance and business stakeholders to ensure contractual terms appropriately address risk, compliance, quality, intellectual property, and business requirements.
- Drive favorable commercial outcomes while maintaining strong supplier partnerships.
Cross-Functional Partnership
- Serve as a trusted advisor to CMC, Supply Chain, and Quality leadership teams.
- Support strategic initiatives including clinical and commercial product launches, technology transfers, manufacturing scale-up activities, and network optimization efforts.
- Collaborate with stakeholders to forecast sourcing needs and align procurement strategies with organizational priorities.
Risk Management & Compliance
- Identify and proactively mitigate supply chain, quality, operational, and financial risks associated with suppliers.
- Support business continuity planning and supplier risk assessments.
- Ensure sourcing activities comply with company policies, industry regulations, and GxP requirements.
Financial Management
- Develop sourcing business cases and total cost of ownership analyses.
- Deliver measurable value through cost savings, cost avoidance, working capital improvements, and supplier performance enhancements.
- Track and report sourcing metrics, savings, and category performance to leadership.
Qualifications
Education
- Bachelor's degree in Supply Chain, Business, Engineering, Life Sciences, Chemistry, or related field required.
- MBA, MS, CPSM, CPM, or equivalent advanced degree/certification preferred.
Experience
- 8+ years of strategic sourcing, procurement, supply chain, or category management experience.
- Minimum 5 years supporting pharmaceutical, biotechnology, or other highly regulated industries.
- Demonstrated experience leading enterprise-level sourcing strategies and complex supplier negotiations.
- Proven ability to design, lead, and execute large and complex RFP processes in highly cross-functional environments.
- Exceptional communication, stakeholder management, and leadership skills, with the ability to influence at all organizational levels.
Preferred Experience
- Experience supporting CMC, Technical Operations, Manufacturing, Supply Chain, and/or Quality organizations.
- Knowledge of GxP regulations, pharmaceutical manufacturing, quality systems, and supply chain operations.
- Experience managing CDMOs and critical supply chain service providers.
Knowledge, Skills & Abilities
- Strong strategic sourcing and category management expertise.
- Proven negotiation and contract management skills.
- Strong understanding of pharmaceutical supply chains and external manufacturing models.
- Ability to influence senior leaders and cross-functional stakeholders without direct authority.
- Excellent analytical, financial modeling, and problem-solving capabilities.
- Experience conducting supplier risk assessments and developing mitigation strategies.
- Strong project management and organizational skills.
- Excellent verbal, written, and presentation communication skills.
- Ability to thrive in a fast-paced, growth-oriented environment.
Leadership Competencies
- Strategic thinker with strong business acumen.
- Collaborative and relationship-focused.
- Results-oriented with a continuous improvement mindset.
- Effective change agent capable of driving organizational adoption.
- Demonstrates integrity, accountability, and sound judgment.
- Balances commercial objectives with quality, compliance, and patient-focused priorities.
Travel
- Approximately 15–25% travel, including supplier visits, manufacturing sites, and industry conferences as needed.
- Position will be based in Zug, Switzerland; Waltham, MA; or West Conshohocken, PA and will require 3 days per week in the office.
Success Measures
- Delivery of annual sourcing savings and value-creation targets.
- Successful implementation of category strategies.
- Supplier performance improvements and risk reduction.
- Timely execution of sourcing support for development, clinical, and commercial programs.
- Strong stakeholder satisfaction and cross-functional partnership effectiveness.
- Maintenance of compliant procurement and supplier management practices.
This role provides a unique opportunity to influence critical supply and quality operations while helping ensure reliable delivery of therapies to patients through strategic supplier partnerships and operational excellence.
We are committed to fostering an inclusive and diverse workplace and do not discriminate on the basis of any legally protected characteristics. Madrigal processes your personal data in connection with its recruitment and talent sourcing activities in accordance with applicable data protection laws. Further information about how your personal data is processed, together with details of your rights and how to exercise them, is available in our Job Applicant Privacy Notice, which is made available to you if you apply through Workday.
Please note that this job description is not exhaustive and may evolve over time. Only shortlisted candidates will be contacted. Applicants must be authorized to work in the country of employment at the time of application. Employment terms, where applicable, will be governed by relevant collective bargaining agreements.
Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.