Associate Director - Preclinical Development, Immunology

<meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Position Summary:&nbsp;</strong></b><span style="font-size:10pt;white-space:pre-wrap;">Terray Therapeutics is seeking a highly motivated, creative, and experienced immunologist to join our biology team. This is a strategic role working closely with the CSO and other leads in the preclinical team and across the company to support our small-molecule pipeline. In this role, the Associate Director will lead the team responsible for all cell-based assay development and execution, including hit validation, structure-activity relationships, and lead optimization. The candidate will provide immunology expertise to evaluate new targets and expand our internal pipeline programs. They will be a pivotal collaborator within a multidisciplinary team. The successful candidate will have a strong background in assay development for inflammation targets in the context of small molecule drug discovery. This role will be full-time, onsite, and will report to the CSO.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">The core responsibilities of this position are:&nbsp;</span></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Lead a small, highly motivated team of assay scientists who develop and run cell assays in support of internal and partner pipeline programs</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Work closely with scientists across the company in biology, chemistry, platform, screening, data, and computational teams to efficiently advance projects from hit validation through hit-to-lead and lead optimization to lead candidate selection</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Develop cell-based assay funnels to support structure-activity optimization for our inflammation target portfolio as programs progress to hit-to-lead and lead optimization</span></li><li style="font-size:10pt;list-style:none;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><ul data-pattern="discCircleSquare" data-depth="2" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin-left:0px;margin-right:0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:circle;"><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Expert understanding of inflammatory pathways as they relate to the target and disease mechanism</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Analyze and interpret experimental data and communicate results in project team meetings</span></li></ul></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Experience and Qualifications:&nbsp;</strong></b><span style="font-size:10pt;white-space:pre-wrap;">Part of Terray’s success is nurtured by a hands-on work environment where everyone is accountable, vested in a vision of excellence, and actively taking part in the success of the business. Terray supports a positive work environment where employees can feel engaged,&nbsp;recognized,&nbsp;and empowered to be creative.&nbsp;They will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><i><em style="font-size:10pt;white-space:pre-wrap;">Required Qualifications:</em></i><span style="font-size:10pt;white-space:pre-wrap;">&nbsp;</span></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">PhD in the small-moleculefield of immunology with 10+ years of small-molecule drug discovery industry experience </span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Deep expertise in immunology, with a strong understanding of immune signaling pathways, disease mechanisms, and immune modulation strategies</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Extensive experience with small-molecule drug development from target validation through lead optimization</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Expertise in evaluating novel targets for drug development, including developing a robust screening approach and desired target product profile</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Strong leadership and mentorship skills with demonstrated experience managing a small team of highly motivated scientists</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Demonstrated ability to collaborate in a multidisciplinary team and drive program progress; comfortable working on multiple projects in parallel and operating within a matrixed structure</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Hands-on experience in developing and optimizing a range on immunological assays (Flow cytometry, cytokine profiling, ELISA, Luminescence/fluorescence-based, Western blot, immunoprecipitation, etc.) and measuring small molecule inhibition (IC50) is required</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Demonstrated technical proficiency, attention to detail, ability to troubleshoot and solve problems, and to deliver high-quality data</span></li><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Excellent organizational, interpersonal, and communication skills,s and can thrive in a highly collaborative research environment</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><i><em style="font-size:10pt;white-space:pre-wrap;">Preferred Qualifications:</em></i></p><ul data-pattern="discCircleSquare" data-depth="1" style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;margin:8px 0px;line-height:1.6;padding:0px 0px 0px 32px;list-style-type:disc;"><li style="font-size:10pt;margin:3px 0px;letter-spacing:0.25px;line-height:1.6;"><span style="font-size:10pt;white-space:pre-wrap;">Hands-on experience with lab automation, high-throughput screening (384-well format), or liquid handling systems is preferred</span></li></ul><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><br></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:10pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:left;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Compensation Details:</strong></b><span style="font-size:10pt;white-space:pre-wrap;">&nbsp;$180,000 - $263,000&nbsp;(annually) depending on skill level; participation in the Company's option plan; 3%&nbsp;retirement safe harbor&nbsp;contribution;&nbsp;fully-paid&nbsp;medical, dental, vision,&nbsp;life,&nbsp;and disability&nbsp;benefits.&nbsp;&nbsp;</span></p> <meta><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><b><strong style="font-size:10pt;white-space:pre-wrap;">Company Overview:</strong></b><span style="font-size:10pt;white-space:pre-wrap;"> Terray Therapeutics is a venture-backed biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic chemistry, automation, and nanotechnology.&nbsp;We’re&nbsp;generating chemical data purpose-built to propel drug discovery into the information age — and&nbsp;we’re&nbsp;doing it on a larger scale and faster than has ever before been possible.&nbsp;</span></p><p style="font-family:&quot;Basel Grotesk&quot;,Arial,sans-serif;font-size:11pt;font-weight:400;line-height:1.6;letter-spacing:0.25px;margin:4px 0px;padding:0px;text-align:justify;"><span style="font-size:10pt;white-space:pre-wrap;">Our closed loop system generates precise chemical datasets at unrivaled scale that work seamlessly with AI to systematically map biochemical interactions between small molecules and causes of disease. Iterative cycles of virtual molecular design and experimentation power AI and machine learning models, which in turn guide the next cycle of design. With a chemistry engine that measures billions of interactions daily and becomes increasingly precise with every cycle, we can answer an unprecedented array of questions — deriving insights that enable us to predictably create drugs for patients in need.&nbsp;</span></p>