(Associate) Director, Clinical Supply Chain

<div class="content-intro"><p>Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation.</p> <p>Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs.</p> <p> </p></div><p><strong>Description of Role</strong></p> <p><span class="TextRun SCXW249916343 BCX0" lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW249916343 BCX0">Centessa is currently </span><span class="NormalTextRun SCXW249916343 BCX0">seeking</span><span class="NormalTextRun SCXW249916343 BCX0"> an (Associate) Director, Clinical Supply Chain. The successful candidate will develop and implement strategies to deliver Clinical Trial Materials (CTM) in support of several clinical programs. Reporting to the Seni</span><span class="NormalTextRun SCXW249916343 BCX0">o</span><span class="NormalTextRun SCXW249916343 BCX0">r Director, Clinical Supply Chain </span><span class="NormalTextRun SCXW249916343 BCX0">t</span><span class="NormalTextRun SCXW249916343 BCX0">his individual will develop strong collaborative relationships with several internal departments as well as third-party procurement, packaging, and distribution providers to align </span><span class="NormalTextRun SCXW249916343 BCX0">objectives</span><span class="NormalTextRun SCXW249916343 BCX0"> and implement decisions which ensure clinical supply. The successful candidate will </span><span class="NormalTextRun SCXW249916343 BCX0">demonstrate</span><span class="NormalTextRun SCXW249916343 BCX0"> strong </span><span class="NormalTextRun SCXW249916343 BCX0">attention to detail, </span><span class="NormalTextRun ContextualSpellingAndGrammarErrorV2Themed SCXW249916343 BCX0">which they</span><span class="NormalTextRun SCXW249916343 BCX0"> will apply to the development and routine maintenance of clinical forecasts, inventory </span><span class="NormalTextRun ContextualSpellingAndGrammarErrorV2Themed SCXW249916343 BCX0">databases</span><span class="NormalTextRun SCXW249916343 BCX0"> and IRT systems providing daily oversight of clinical supplies. Management and travel to CDMOs both domestically and internationally may be </span><span class="NormalTextRun SCXW249916343 BCX0">required</span><span class="NormalTextRun SCXW249916343 BCX0">.</span></span><span class="EOP SCXW249916343 BCX0" data-ccp-props="{}"> </span></p> <p><strong>Key Responsibilities</strong></p> <p><strong><span data-contrast="auto">Leadership:</span></strong><span data-ccp-props="{}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1"><span data-contrast="auto">Develop and update clinical supply strategies as needed to meet corporate demands</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Develop/maintain strong collaborative relationships with internal departments and external CDMOs</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Identify potential supply chain risks and develop & implement negotiated mitigation strategies</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Manage study/program budget, contracts and change orders and track spend against budget</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Drive process optimization, scalability, and implementation of best practices and systems.<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong><span data-contrast="auto">Execution:</span></strong><span data-ccp-props="{"201341983":2,"335559685":360,"335559740":23}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1"><span data-contrast="auto">Develop and working with Clinical, regularly update forecast/demand plans for finished goods and work with Manufacturing to develop production schedules which meet clinical demand.</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Collaborate with Quality, Clinical, CMC and external CDMOs to develop and approve clinical labels.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Manage CDMO packaging/labeling schedules to ensure availability of clinical supplies.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Interact regularly with third-party providers to manage logistics & licenses required to ship materials from manufacturing to bulk storage facilities, courier depots and investigator sites.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Work with CMC and QA to facilitate document transfer required for CTM/QP release by CDMOs</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Manage and track clinical supply inventory either manually or through an Interactive Response Technology (IRT) system.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Manage Product Recovery pending investigation of CTM from investigator sites as needed.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="6" data-aria-level="1">Support supply risk mitigation planning (e.g., shortages, delays, temperature excursions).<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong><span data-contrast="auto">Collaboration:</span></strong><span data-ccp-props="{"201341983":2,"335559685":360,"335559740":23}"> </span></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1"><span data-contrast="auto">Contribute to SOP development, maintenance, and continuous improvement initiatives.</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Effectively collaborate and communication across multiple functional areas, bringing a sufficient breadth of knowledge.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Monitor shelf-life and expiry dating and coordinate retest extension with analytical team to ensure continuous supply.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Manage investigation, reporting and communication of outcomes from temperature excursions and product complaints.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Author and/or review supply chain sections of regulatory submissions</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">If required, participate as SME in audits or for-cause inspection of CDMOs.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Contribute as a SME to CDMO selection and approval process and review of associated Master Service Agreements (MSA) and Quality Agreements for clinical supply services</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="14" data-aria-level="1">Represent Supply Chain in Clinical and CMC Sub Team meetings<span data-ccp-props="{"201341983":0,"335559739":120,"335559740":240,"469777462":[720],"469777927":[0],"469777928":[0]}"> </span></li> </ul> <p><strong>Qualifications</strong></p> <ul> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1"><span data-contrast="auto">Bachelor’s degree in engineering or science is required</span></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">8-10 years of biotech/pharma industry experience in clinical supply <em>with <span style="text-decoration: underline;">significant</span> international experience is required</em></li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Experience in all aspects of clinical supply chain as well as a deep understanding of GMP/GDP</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Requires a strong understanding of managing groups, CMOs and CDMOs</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1"> <div>Experience overseeing or managing blistering and walleting packaging processes required. </div> </li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1"> <div>Proven background in working with small molecule modality required</div> </li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1"> <div>Demonstrated experience operating within a commercial drug product environment</div> </li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Strong organizational, analytical, decision-making and interpersonal skills</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Ability to work on multiple projects independently in a fast-paced dynamic environment</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Demonstrated ability to coordinate CDMO activities in the development and commercialization of pharmaceutical products</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Excellent organizational skills, project management skills and detail-orientated leadership approach</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Ability to thrive in a small company culture and assist in creating and implementing processes.</li> <li data-leveltext="" data-font="Symbol" data-listid="8" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="22" data-aria-level="1">Willing and able to travel both domestically and internationally </li> </ul> <p><strong><span data-contrast="auto">Compensation</span></strong><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">The annual base salary range for the Associate Director, Supply Chain position is $170,000 - $205,000. </span></p> <p><span data-contrast="auto">The annual base salary range for the Director, Supply Chain position is $190,000 - $230,000.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, and job knowledge.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">In addition to base pay, this role is eligible for a discretionary annual bonus and participation in our equity program, allowing you to share in Centessa’s long-term success.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">Centessa also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.</span><span data-ccp-props="{}"> </span></p> <p><strong>Work Location</strong></p> <p>The (Associate) Director, Clinical Supply Chain is a remote role based in the US, with occasional travel (up to 20%)</p> <p><strong>POSITION:</strong> Full-Time, Exempt</p><div class="content-conclusion"><p>EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.</p> <p><strong><span class="break-words tvm-parent-container">Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.</span></strong></p></div>