Description

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.Associate Director, Clinical OutsourcingPosition SummaryThe Associate Director, Clinical R&D Outsourcing is responsible for assisting in the management all aspects of vendor contracting, site contracting, and negotiation / execution of all required agreements in support of the clinical plan. This role partners closely with Clinical Operations and cross-functional stakeholders to ensure CROs and external vendors deliver high-quality, compliant, and cost-effective clinical trial execution. The role combines strategic oversight with hands-on vendor management across all phases of clinical development.Key Responsibilities<ul><li>Serve as the primary outsourcing lead for assigned clinical programs and trials</li></ul><ul><li>Lead CRO and ancillary vendor selection activities, including RFP development, bid analysis, and negotiation</li><li>Negotiate clinical scopes of work, budgets, payment milestones, and change orders in collaboration with Legal, Finance, and Procurement</li></ul><ul><li>Ensure contracts and amendments support protocol requirements and operational needs</li><li>Identify and implement cost-optimization opportunities while maintaining trial quality and timelines</li></ul><ul><li>Partner closely with Clinical Operations, Clinical Development, Data Management, Biostatistics, Regulatory, Quality, and Project Management</li><li>Provide outsourcing expertise to study teams from protocol development through study close-out</li><li>Support inspection readiness, audits, and CAPA activities related to CROs and other clinical vendors</li></ul>QualificationsEducation<ul><li>Bachelor’s degree required</li></ul>Experience<ul><li>10+ years of experience in clinical outsourcing</li><li>Demonstrated experience managing CROs/ancillary vendors across Phase I–III clinical trials (Phase IV a plus)</li><li>Strong track record in clinical contract negotiation, budget management, and vendor oversight</li></ul>Skills & Competencies<ul><li>Deep understanding of clinical trial operations and ICH/GCP requirements</li><li>Strong negotiation, communication, and stakeholder management skills</li><li>Ability to manage multiple studies and vendors in parallel</li><li>Detail-oriented, proactive, and comfortable operating in a fast-paced clinical environment</li></ul>Working Conditions<ul><li>This position is intended to be in the office three days a week but there is the potential to be flexible on an ‘as needed’ basis. A limited amount of travel will be required for in-person meetings.</li></ul>Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. The base salary range for this position is $169,000 - $206,000 per year.All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Applications are being accepted on an ongoing basis and can be submitted through our <a target="_blank" href="https://madrigalpharma.wd501.myworkdayjobs.com/Madrigal">Madrigal Careers</a> site. Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to <a target="_blank" href="mailto:HR@madrigalpharma.com">HR@madrigalpharma.com</a>.

Associate Director, Clinical Outsourcing

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Madrigal Pharmaceuticals

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