Associate Director, Clinical Development

<p>Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.</p> <p><strong>The Opportunity:</strong></p> <p>We are seeking an experienced clinical scientist to serve as Associate Director, Clinical Science in support of Revolution Medicines’ late-stage clinical programs.  In this role, you will independently lead defined clinical science workstreams within pivotal and supportive studies and support execution of the registrational clinical development strategy for assigned molecule(s) and indication(s). The Associate Director plays a critical role in ensuring high-quality clinical data review, protocol consistency, and submission-readiness for late-stage programs. This position operates with substantial autonomy within assigned scope and collaborates closely with more senior clinical science team members and the study Medical Director to ensure medically sound and regulatory-aligned execution. Furthermore:</p> <ul> <li> <p>Independently lead defined clinical science workstreams within pivotal and registration-enabling studies (e.g., endpoint strategy, data review oversight, CSR section ownership, data consistency initiatives).</p> </li> <li> <p>Contribute substantially to protocol development, CRF design, ICF updates, and alignment of data standards with downstream regulatory requirements.</p> </li> <li> <p>Drive ongoing clinical data review activities, including plausibility review, query trend analysis, and preparation for database lock.</p> </li> <li> <p>Accountable for assigned clinical science deliverables supporting regulatory submissions, including CSR sections, briefing package content, and health authority response inputs.</p> </li> <li> <p>Support preparation of regulatory documentation and responses to health authority questions.</p> </li> <li> <p>Collaborate closely with Biostatistics, Data Management, Medical Writing, Medical Directors, Pharmacovigilance, and Clinical Operations to ensure alignment and submission readiness.</p> </li> <li> <p>Participate in study team meetings and represent Clinical Science in sub-team discussions.</p> </li> <li> <p>May serve as Clinical Science lead for smaller or supportive studies, based on experience and study complexity.</p> </li> <li> <p>Mentor Senior Clinical Scientists and Clinical Scientists as appropriate.</p> </li> <li> <p>Proactively identify risks, propose mitigation strategies, and escalate significant issues as appropriate to Directors or Senior Directors.</p> </li> <li> <p>Contribute to cross-functional discussions to support eSective and eSicient study execution.</p> </li> </ul> <p><strong>Required Skills, Experience and Education: </strong></p> <ul> <li> <p>Bachelor’s Degree (life sciences preferred); Advanced Clinical/Science Degree is a plus (e.g., PharmD, PhD, MSN, MPH, etc.).</p> </li> <li> <p>5+ years of clinical development or relevant experience within a pharmaceutical, biotech, or academic clinical research setting; late-stage development experience preferred.</p> </li> <li> <p>Demonstrated experience contributing to pivotal or registration-enabling studies.</p> </li> <li> <p>Strong knowledge of GCP, ICH, FDA, EMA, and other relevant regulatory guidelines.</p> </li> <li> <p>Experience contributing to protocol development, CRF design, and regulatory documentation.</p> </li> <li> <p>Strong analytical skills and experience interpreting clinical trial data.</p> </li> <li> <p>Proven ability to work eSectively in cross-functional teams and integrate multiple perspectives.</p> </li> <li> <p>Excellent written and verbal communication skills.</p> </li> <li> <p>Strong organizational skills and ability to manage multiple deliverables.</p> </li> </ul> <p><strong>Preferred Skills: </strong></p> <ul> <li> <p>Experience contributing to NDA/BLA/MAA submission components.</p> </li> <li> <p>Experience supporting health authority interactions.</p> </li> <li> <p>Demonstrated ability to lead defined study-level initiatives.</p> </li> <li> <p>Experience mentoring junior clinical science staffs.</p> </li> </ul> <p class="p1"><span style="color: rgb(255, 255, 255);">#LI-Hybrid  #LI-SH1</span></p><div class="content-pay-transparency"><div class="pay-input"><div class="description"><p>The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.</p> <p>Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.</p> <p>Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.</p> <p>Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our <a href="https://www.revmed.com/ccpa-notice">CCPA Notice</a> and <a href="https://www.revmed.com/privacy-policy">Privacy Policy</a>. For additional information, please contact <a href="mailto:privacy@revmed.com">privacy@revmed.com</a>.</p></div><div class="title">Base Pay Salary Range</div><div class="pay-range"><span>$186,000</span><span class="divider">—</span><span>$233,000 USD</span></div></div></div><div class="content-conclusion"><hr> <p><em>We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.</em><br><em> </em><br><em>Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official <strong>@revmed.com</strong> email address.</em><br><em> </em><br><em>If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to <span style="color: rgb(35, 111, 161);"><strong>careers@revmed.com</strong></span> so we can share these impersonations with our IT team for tracking and awareness.</em></p> <hr> <p> </p></div>