Associate Director, Biostatistics

We are seeking an Associate Director of Biostatistics to provide statistical expertise and operational support across a variety of clinical activities with a focus on supporting early-stage and late-stage clinical programs.  This role will serve as lead study statistician, collaborating with cross-functional teams to support clinical development and data-driven decision-making. The Associate Director will contribute hands-on to key deliverables, manage CROs, and provide guidance to junior team members. 

 

Essential Responsibilities:

• Contribute to the statistical design and analysis of early and late phase clinical studies. 
• Apply advanced statistical methods and data visualization skills to clinical trial data summaries and interpretations such as integrated safety and efficacy analyses for regulatory submissions. 
• Serve as the biostatistics representative on cross-functional teams, ensuring alignment of statistical approaches with study and program objectives. 
• Provide input on study design, endpoint selection, and sample size planning. 
• Draft statistical analysis plans (SAPs) and support interpretation of results. 
• Ensure the quality and accuracy of statistical deliverables by independently generating the statistical deliverables and/or independently reviewing and validating the statistical deliverables generated by either CRO or internal statistical programming team. 
• Manage CROs and mentor junior staff or contractors as appropriate. 

The Ideal Candidate:

Education: 

• Ph.D. in Biostatistics with 6+ years of relevant industry experience, or Master’s with 8+ years.

Experience: 

• Significant experience serving as a study statistician on global Phase III clinical trials, ideally in immunology or immune-mediated diseases.
• Demonstrated track record of supporting regulatory submissions (NDA/BLA/MAA), including integrated safety/efficacy analyses.
• Hands-on experience working in a biotechnology or pharmaceutical company environment (not only CRO, Site, or Academic).
• Proven ability to manage CROs and statistical programming teams in a sponsor setting.
• Strong foundation in clinical trial design, statistical analysis, and regulatory guidelines.
• Proficiency in statistical programming (SAS and R).
• Experience in publication work and/or analysis of real-world data preferred. 
• Demonstrated ability to manage multiple priorities and work cross-functionally. 
• Experience with both early-stage and late-phase clinical trials. 

Skills: 

• Strong analytical thinking and attention to detail. 
• Excellent verbal and written communication skills. 
• Ability to work independently in a fast-paced, regulated environment. 
• Ability to manage deliverables with competing priorities and influence others effectively. 
• Strong organizational skills, with the ability to manage workflows and activities to meet department timelines. 
• Collaborative mindset and ability to influence without authority. 

 

The salary range for this position is $190,000 USD to $230,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

This position is located in South San Francisco, CA, with an expectation to be onsite Tuesday through Thursday. While we prefer local candidates, remote applicants based in the Pacific Time Zone will be considered on a case-by-case basis.

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  

Other benefits include:

• Health insurance premiums paid at 90% for employee, 80% for dependents
• Free access to Genentech Bus & Ferry Share program
• $100 monthly cell phone stipend
• Unlimited PTO for Exempt employees
• Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.