2026 Summer Intern – DMPK (Graduate student)

<div class="content-intro"><p><strong><span data-contrast="auto">About Us</span></strong><span data-ccp-props="{}"> </span></p> <div data-olk-copy-source="MessageBody">Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.<br><br></div> <div>It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.</div> <div> </div> <div>Led by Tassos Giannakakos, Jay Edelberg, <span data-olk-copy-source="MessageBody">M.D., Ph.D.,</span> and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.</div> <div> </div> <div>We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.</div> <div> </div> <div>At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. <strong>Driven by patients and their families</strong>, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in <strong>being authentic</strong>—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an <strong>eagerness to learn</strong>, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to <strong>winning as a team</strong> with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to <strong>enable the impossible</strong> because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.</div> <div> </div> <div>These values are the foundation of our work, empowering us to make a real difference, every day.</div> <div> </div> <div> </div></div><p><strong>Position Title: </strong>2026 Summer Intern – DMPK (Graduate student)</p> <p><strong>Department: </strong>Drug Metabolism and Pharmacokinetics</p> <p><strong>Reports To:</strong> Principal Scientist</p> <p><strong>Location: </strong>South San Francisco, CA 5 days per week (Mon to Fri)</p> <p><strong> </strong></p> <p><strong>Job Overview</strong></p> <p> </p> <p>Kardigan is looking for a scientific intern to join our DMPK team and gain hands-on exposure to a wide range of activities including assisting in characterizing the metabolic stability and reactive metabolites of small molecules, gaining experience in LC-MS and in-vitro DMPK assays.  If you’re interested in developing analytical skills within a supportive and fast-moving environment, this role is a great fit.  You’ll learn from experienced teammates and make a meaningful impact on our department.</p> <p> </p> <p><strong>What You’ll Do</strong></p> <p> </p> <ul> <li>Hands-on lab work on metabolite characterization using HPLC and high-resolution LC-MS along with other various lab equipment.</li> <li>Assist in the development of in-vitro DMPK assays including work with transporters and drug metabolizing enzymes.</li> <li>The work will involve data analysis and scientific literature review.</li> <li>Present data at weekly meetings</li> <li>Prepare and present the findings of the internship at the end of summer research meeting.</li> </ul> <p> </p> <p><strong>Qualifications</strong></p> <p> </p> <ul> <li>Pursuing a Master's degree in Chemistry, Biochemistry, Pharmacology, or related field at an accredited university.</li> <li>Basic knowledge of pipetting and lab safety is required.</li> <li>Have a theoretical understanding of mass spectrometry and chromatography.</li> <li>This position is ideal for someone who is passionate about drug discovery and eager to learn from leaders in the group.</li> <li>Ideal candidate will have the ability to interpret and analyze experimental data, troubleshoot experiments, and propose solutions to challenges.</li> </ul> <p> </p> <p><span data-teams="true"><strong>Pay:</strong> $35 per hour<br><strong>Location requirement:</strong> Candidates must be based in the San Francisco Bay Area (no relocation assistance)</span></p> <p> </p>