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Zollinger-Ellison Syndrome

3
Pipeline Programs
2
Companies
2
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
2
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

AstraZeneca
NEXIUMApproved
esomeprazole magnesium
AstraZeneca
oral2001
74M Part D
AstraZeneca
NEXIUM 24HRApproved
esomeprazole magnesium
AstraZeneca
oral2015

Competitive Landscape

2 companies ranked by most advanced pipeline stage

AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
1
Esomeprazole magnesiumPhase 31 trial
Active Trials
NCT00079833Completed25Est. Jul 2005
Trio Medicines
Trio MedicinesUK - London
1 program
YF476PHASE_21 trial
Active Trials
NCT02454075Terminated3Est. Jun 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AstraZenecaEsomeprazole magnesium
Trio MedicinesYF476

Clinical Trials (2)

Total enrollment: 28 patients across 2 trials

NCT00079833AstraZenecaEsomeprazole magnesium

Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome

Start: Nov 2003Est. completion: Jul 200525 patients
Phase 3Completed

YF476 and Type II Gastric Carcinoids

Start: Apr 2011Est. completion: Jun 20123 patients
Phase 2Terminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.