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X-Linked Retinitis Pigmentosa (XLRP)

2
Pipeline Programs
2
Companies
2
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Gene Therapy
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Beacon Therapeutics
Beacon TherapeuticsMA - Cambridge
1 program
1
Adeno-associated virus vector expressing a human RPGR genePhase 2Gene Therapy1 trial
Active Trials
NCT07174726Recruiting10Est. Dec 2030
Frontera Therapeutics
Frontera TherapeuticsChina - Suzhou
1 program
1
FT-002Phase 1/21 trial
Active Trials
NCT06492850Recruiting32Est. Feb 2026

Trial Timeline

Clinical trial activity over time

2024
2025
2026
2027
2028
2029
2030
Beacon TherapeuticsAdeno-associated virus vector expressing a human RPGR gene
Frontera TherapeuticsFT-002

Clinical Trials (2)

Total enrollment: 42 patients across 2 trials

NCT07174726Beacon TherapeuticsAdeno-associated virus vector expressing a human RPGR gene

A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis Pigmentosa

Start: Sep 2025Est. completion: Dec 203010 patients
Phase 2Recruiting

Gene Therapy for RPGR Gene Mutation-associated X-linked Retinitis Pigmentosa

Start: Apr 2024Est. completion: Feb 202632 patients
Phase 1/2Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 42 patients
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.