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Ventral Hernia

3
Pipeline Programs
9
Companies
13
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
1
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

8 companies ranked by most advanced pipeline stage

Medtronic
MedtronicNJ - Phillipsburg
5 programs
1
Strattice biologic meshPhase 2/31 trial
MaxTack™ Motorized Fixation DeviceN/A1 trial
Parietene DS Composite MeshN/A1 trial
mesh fixation by transfacial suturesN/A1 trial
permanent mesh fixationN/A1 trial
Active Trials
NCT06710795Active Not Recruiting35Est. May 2027
NCT03495154Completed145Est. Jul 2022
NCT00773851Completed36Est. Oct 2008
+2 more trials
AbbVie
AbbVieNORTH CHICAGO, IL
2 programs
2
AGN-151607-DPPhase 2
BOTOX Dose APhase 21 trial
Active Trials
NCT05606757Withdrawn0Est. Sep 2025
Intuitive Surgical
Intuitive SurgicalCA - Sunnyvale
3 programs
Open retromuscular ventral hernia repairN/A1 trial
Robotic Ventral Hernia Repair with IPOMN/A1 trial
robotic-assisted ventral hernia repairN/A1 trial
Active Trials
NCT04487522Completed74Est. Sep 2024
NCT03283982Completed75Est. Jan 2021
NCT04855227Terminated69Est. Nov 2024
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
AlvimopanN/A
MSD
MSDIreland - Ballydine
1 program
AlvimopanN/A1 trial
Active Trials
NCT02379858Terminated10Est. May 2018
Momentis Surgical
Momentis SurgicalIsrael - Or Yehuda
1 program
Robotic Ventral Hernia RepairN/A1 trial
Active Trials
NCT06457971Recruiting50Est. Dec 2025
Stryker
StrykerCA - San Jose
1 program
SPY - Unblinded use of SPY EliteN/A1 trial
Active Trials
NCT01886963Completed115Est. Oct 2015
Johnson & Johnson
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
use of a tissue separating meshN/A1 trial
Active Trials
NCT00572962Completed210Est. Aug 2014

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
MedtronicStrattice biologic mesh
AbbVieBOTOX Dose A
MedtronicMaxTack™ Motorized Fixation Device
Momentis SurgicalRobotic Ventral Hernia Repair
Intuitive Surgicalrobotic-assisted ventral hernia repair
Intuitive SurgicalOpen retromuscular ventral hernia repair
MedtronicParietene DS Composite Mesh
Intuitive SurgicalRobotic Ventral Hernia Repair with IPOM
MSDAlvimopan
StrykerSPY - Unblinded use of SPY Elite
Medtronicpermanent mesh fixation
Johnson & Johnsonuse of a tissue separating mesh
Medtronicmesh fixation by transfacial sutures

Clinical Trials (13)

Total enrollment: 1,014 patients across 13 trials

NCT02703662MedtronicStrattice biologic mesh

Performance of Biologic Mesh Materials in Abdominal Wall Reconstruction

Start: Oct 2017Est. completion: Dec 202590 patients
Phase 2/3Unknown
NCT05606757AbbVieBOTOX Dose A

A Study to Evaluate Adverse Events and Effectiveness of OnabotulinumtoxinA in Participants Undergoing Open Abdominal Ventral Hernia Repair for the Achievement of Primary Fascial Closure Without the Use of Component Separation Technique

Start: May 2024Est. completion: Sep 20250
Phase 2Withdrawn
NCT06710795MedtronicMaxTack™ Motorized Fixation Device

AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair

Start: Jun 2025Est. completion: May 202735 patients
N/AActive Not Recruiting
NCT06457971Momentis SurgicalRobotic Ventral Hernia Repair

Anovo Surgical System in Ventral Hernia

Start: Jan 2024Est. completion: Dec 202550 patients
N/ARecruiting
NCT04855227Intuitive Surgicalrobotic-assisted ventral hernia repair

A Prospective Evaluation of Pain After Non-complex Ventral Hernia Repair

Start: Aug 2021Est. completion: Nov 202469 patients
N/ATerminated
NCT04487522Intuitive SurgicalOpen retromuscular ventral hernia repair

Pain and Quality of Life After Retromuscular Ventral Hernia Repair (RECOVER)

Start: Jul 2020Est. completion: Sep 202474 patients
N/ACompleted
NCT03495154MedtronicParietene DS Composite Mesh

Post Market Study of Parietene™ DS Composite Mesh in Ventral Hernia Repair

Start: Jun 2018Est. completion: Jul 2022145 patients
N/ACompleted
NCT03283982Intuitive SurgicalRobotic Ventral Hernia Repair with IPOM

Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM

Start: Sep 2017Est. completion: Jan 202175 patients
N/ACompleted

Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair

Start: Jul 2015Est. completion: May 201810 patients
N/ATerminated
NCT01886963StrykerSPY - Unblinded use of SPY Elite

A Clinical Trial Using Spy Elite System in Planning Tissue Advancement Flaps After Ventral Hernia Repair

Start: Nov 2011Est. completion: Oct 2015115 patients
N/ACompleted
NCT01109771Medtronicpermanent mesh fixation

Absorbable Versus Permanent Mesh Fixation Trial in Laparoscopic Midline Ventral Hernia Repair

Start: Apr 2010Est. completion: Aug 2015105 patients
N/ACompleted
NCT00572962Johnson & Johnsonuse of a tissue separating mesh

Prospective Clinical Observational Cohort Study to Evaluate the Use of a Tissue Separating Mesh (Proceed®) in Laparoscopic Ventral Hernia Repair

Start: Jan 2008Est. completion: Aug 2014210 patients
N/ACompleted
NCT00773851Medtronicmesh fixation by transfacial sutures

Transfacial Sutures Versus Stapler for Mesh Fixation in Laparoscopic Ventral Hernia Repair

Start: Apr 2005Est. completion: Oct 200836 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 1,014 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.