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Venous Leg Ulcer (VLU)

1
Pipeline Programs
6
Companies
5
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Serena Group
Serena GroupMA - Cambridge
1 program
1
Intact Fish Skin GraftPhase 4
ConvaTec
ConvaTecNJ - Bridgewater
1 program
ConvaVAC™ Ag+ Negative Pressure Wound Therapy SystemN/A1 trial
Active Trials
NCT07342049Recruiting87Est. Oct 2026
Omeza
OmezaFL - Sarasota
1 program
Omeza OCM™ Wound MatrixN/A1 trial
Active Trials
NCT07754526Not Yet Recruiting254Est. Dec 2028
Biolab Pharma
Biolab PharmaBrazil - São Paulo
1 program
Tri-Membrane Wrap™N/A1 trial
Active Trials
NCT07078968Completed500Est. Oct 2025
MediWound
MediWoundYAVNE, Israel
1 program
EscharExPHASE_31 trial
Active Trials
NCT06568627Recruiting216Est. Mar 2027
Kerecis
KerecisIceland - Isafjordur
1 program
Intact Fish Skin GraftPHASE_41 trial
Active Trials
NCT06693570Recruiting150Est. Nov 2026

Trial Timeline

Clinical trial activity over time

2024
2025
2026
2027
2028
KerecisIntact Fish Skin Graft
MediWoundEscharEx
OmezaOmeza OCM™ Wound Matrix
ConvaTecConvaVAC™ Ag+ Negative Pressure Wound Therapy System
Biolab PharmaTri-Membrane Wrap™

Clinical Trials (5)

Total enrollment: 1,207 patients across 5 trials

NCT06693570KerecisIntact Fish Skin Graft

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

Start: Nov 2024Est. completion: Nov 2026150 patients
Phase 4Recruiting

A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

Start: Jun 2025Est. completion: Mar 2027216 patients
Phase 3Recruiting
NCT07754526OmezaOmeza OCM™ Wound Matrix

OCM™ Treatment With Routine Care in Venous Leg Ulcers Compared to Routine Care Treatment Alone.

Start: Aug 2026Est. completion: Dec 2028254 patients
N/ANot Yet Recruiting
NCT07342049ConvaTecConvaVAC™ Ag+ Negative Pressure Wound Therapy System

ConvaVAC™ Ag+ Negative Pressure Wound Therapy System in Chronic Wounds

Start: Jan 2026Est. completion: Oct 202687 patients
N/ARecruiting
NCT07078968Biolab PharmaTri-Membrane Wrap™

A Real World Data Collection of Human Amniotic Membrane(s) on Diabetic Foot Ulcers, Venous Leg Ulcers, Pressure Ulcers and Post Operative Wounds

Start: Apr 2025Est. completion: Oct 2025500 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 actively recruiting trials targeting 1,207 patients
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.