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Various

0
Pipeline Programs
7
Companies
50
Clinical Trials
16 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
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Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
150%
Monoclonal Antibody
150%
+ 10 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Bristol Myers Squibb
4 programs
Anti-IL8N/A1 trial
BET InhibitorN/A1 trial
IberdomideN/A5 trials
RelatlimabN/AMonoclonal Antibody5 trials
Active Trials
NCT05210894No Longer Available
NCT05301972No Longer Available
NCT07434960Available
+9 more trials
Incyte
IncyteDE - Wilmington
3 programs
INCB052793N/A1 trial
INCB054329N/A1 trial
PemigatinibN/ASmall Molecule1 trial
Active Trials
NCT03906344No Longer Available
NCT03896815No Longer Available
NCT03906357No Longer Available
Cook MyoSite
Cook MyoSitePA - Pittsburgh
1 program
Autologous Muscle Derived CellsN/A1 trial
Active Trials
NCT04661293Temporarily Not Available
CSL Behring
CSL BehringIL - Bradley
1 program
CSL830N/A1 trial
Active Trials
NCT03177005Approved For Marketing
CSL Seqirus
CSL SeqirusUK - Maidenhead
1 program
CSL830N/A
Occlutech
OcclutechSwitzerland - Schaffhausen
1 program
Catheter implantation of Occlutech AFR deviceN/A1 trial
Active Trials
NCT07421557Available
Amgen
AmgenTHOUSAND OAKS, CA
1 program
UPLIZNAN/A1 trial
Active Trials
NCT06590051Available

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbIberdomide
Bristol Myers SquibbIberdomide
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbIberdomide
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbIberdomide
Bristol Myers SquibbRelatlimab
Bristol Myers SquibbIberdomide
Bristol Myers SquibbRelatlimab

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 8,598 patients across 50 trials

A Study To Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Untreated, Unresectable or Metastatic Melanoma Participants In India

Start: Nov 2026Est. completion: May 202930 patients
Phase 4Not Yet Recruiting

A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma

Start: Mar 2023Est. completion: Nov 2027579 patients
Phase 3Active Not Recruiting

NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide

Start: Oct 2022Est. completion: Apr 2029480 patients
Phase 3Not Yet Recruiting

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Start: Jun 2022Est. completion: Jun 2032939 patients
Phase 3Active Not Recruiting

A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer

Start: Apr 2022Est. completion: Jul 2025770 patients
Phase 3Terminated

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

Start: Apr 2018Est. completion: Dec 2030714 patients
Phase 2/3Active Not Recruiting

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

Start: Feb 2026Est. completion: Jan 2038494 patients
Phase 2Recruiting

Isatuximab and Iberdomide as Immunotherapy for High Risk in Smouldering Myeloma

Start: Jun 2025Est. completion: Nov 203263 patients
Phase 2Recruiting

A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

Start: Mar 2025Est. completion: Dec 202815 patients
Phase 2Recruiting

Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma

Start: Jun 2024Est. completion: Jul 203620 patients
Phase 2Recruiting

Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma

Start: Mar 2024Est. completion: Apr 203420 patients
Phase 2Recruiting

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma

Start: Feb 2024Est. completion: Mar 203130 patients
Phase 2Recruiting

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

Start: Feb 2024Est. completion: Aug 202890 patients
Phase 2Recruiting

Iberdomide and Daratumumab As Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma

Start: Dec 2023Est. completion: Dec 202660 patients
Phase 2Recruiting

A Study to Evaluate Whether Participants With Melanoma Prefer Subcutaneous vs Intravenous Administration of Nivolumab and Nivolumab + Relatlimab Fixed-dose Combinations

Start: Nov 2023Est. completion: Aug 2027100 patients
Phase 2Active Not Recruiting

A Phase 2 Clinical Trial of Neoadjuvant Relatlimab and Nivolumab in High Risk, Clinical Stage II Cutaneous Melanoma

Start: Aug 2023Est. completion: Oct 203520 patients
Phase 2Active Not Recruiting

Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.

Start: Sep 2022Est. completion: Dec 2029140 patients
Phase 2Not Yet Recruiting

Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma

Start: Jul 2021Est. completion: Sep 202968 patients
Phase 2Recruiting

Iberdomide Combined With Low-dose Cyclophosphamide and Dexamethasone

Start: Feb 2021Est. completion: Dec 202760 patients
Phase 2Active Not Recruiting

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors

Start: Feb 2021Est. completion: Nov 2025266 patients
Phase 2Completed

Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma

Start: Nov 2020Est. completion: Jan 202627 patients
Phase 2Completed

Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study

Start: Feb 2020Est. completion: Mar 202668 patients
Phase 2Completed

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

Start: Dec 2019Est. completion: Oct 202680 patients
Phase 2Active Not Recruiting

An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Start: Oct 2019Est. completion: Sep 20240
Phase 2Withdrawn

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Start: Feb 2019Est. completion: Sep 202459 patients
Phase 2Completed

Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression

Start: Jan 2019Est. completion: May 20202 patients
Phase 2Terminated

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Start: Nov 2018Est. completion: Oct 202638 patients
Phase 2Active Not Recruiting

Nivolumab for Treatment of Squamous Cell Carcinoma of the Skin

Start: Mar 2017Est. completion: Dec 202761 patients
Phase 2Recruiting

A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma

Start: Feb 2017Est. completion: Nov 2021182 patients
Phase 2Completed

A Study to Test Combination Treatments in Participants With Advanced Gastric Cancer

Start: Nov 2016Est. completion: May 2022190 patients
Phase 2Completed

An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer

Start: May 2016Est. completion: Jan 2020295 patients
Phase 2Terminated

Saci Nivo Rela for TNBC

Start: Dec 2025Est. completion: Dec 203060 patients
Phase 1/2Recruiting

A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Start: Feb 2025Est. completion: Jan 2029413 patients
Phase 1/2Recruiting

Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

Start: Nov 2024Est. completion: Dec 203449 patients
Phase 1/2Recruiting

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma

Start: Sep 2022Est. completion: Dec 20255 patients
Phase 1/2Completed

A Study of Nivolumab and Relatlimab in Combination With Bevacizumab in Advanced Liver Cancer

Start: May 2022Est. completion: Nov 202583 patients
Phase 1/2Completed

A Study to Assess Relatlimab and Nivolumab Fixed-dose Combination in Chinese Participants With Advanced Solid Tumors

Start: Nov 2021Est. completion: Oct 202524 patients
Phase 1/2Completed

Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma

Start: Oct 2021Est. completion: Apr 20290
Phase 1/2Withdrawn

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer

Start: Mar 2019Est. completion: Dec 202621 patients
Phase 1/2Active Not Recruiting

An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors

Start: Nov 2013Est. completion: Feb 20251,482 patients
Phase 1/2Completed

Talquetamab in Combination With Iberdomide and Dexamethasone for Relapsed or Refractory Multiple Myeloma

Start: Jul 2025Est. completion: Jul 202932 patients
Phase 1Recruiting

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Start: Feb 2024Est. completion: Aug 2028147 patients
Phase 1Recruiting

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Start: Jun 2023Est. completion: Aug 20241 patients
Phase 1Completed

A Study of Iberdomide (CC-220) in Combination With Elotuzumab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

Start: Feb 2023Est. completion: Dec 20267 patients
Phase 1Active Not Recruiting

Study of Relatlimab in Combination With Nivolumab in Chinese Participants

Start: Jul 2022Est. completion: Jan 20246 patients
Phase 1Completed

Study of Novel Regimens in Relapsed or Refractory Multiple Myeloma

Start: May 2022Est. completion: Nov 202316 patients
Phase 1Terminated

A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment

Start: Dec 2021Est. completion: Jul 202311 patients
Phase 1Terminated

Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma

Start: Sep 2021Est. completion: Dec 2028224 patients
Phase 1Recruiting

Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function

Start: Aug 2021Est. completion: Jan 202326 patients
Phase 1Completed

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

Start: May 2021Est. completion: Jun 203031 patients
Phase 1Active Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

16 actively recruiting trials targeting 8,598 patients
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.