Urolithiasis

0
Pipeline Programs
2
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 3 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Calyxo
CalyxoCA - Pleasanton
3 programs
CVAC® SYSTEMN/A1 trial
CVAC® SYSTEMN/A1 trial
Steerable Ureteroscopic Renal EvacuationN/A1 trial
Active Trials
NCT07225933Active Not Recruiting3,000Est. Sep 2026
NCT07155005Not Yet Recruiting1,000Est. Apr 2029
NCT07101809Not Yet Recruiting150Est. Sep 2029
Genesis Therapeutics
Genesis TherapeuticsCA - Burlingame
1 program
CiprofloxacinN/ASmall Molecule1 trial
Active Trials
NCT02944825CompletedEst. Mar 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
CalyxoCVAC® SYSTEM
CalyxoSteerable Ureteroscopic Renal Evacuation
CalyxoCVAC® SYSTEM
Genesis TherapeuticsCiprofloxacin

Clinical Trials (4)

Total enrollment: 4,150 patients across 4 trials

NCT07155005CalyxoCVAC® SYSTEM

Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence Study

Start: Mar 2026Est. completion: Apr 20291,000 patients
N/ANot Yet Recruiting
NCT07101809CalyxoSteerable Ureteroscopic Renal Evacuation

Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology

Start: Sep 2025Est. completion: Sep 2029150 patients
N/ANot Yet Recruiting
NCT07225933CalyxoCVAC® SYSTEM

A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System

Start: Feb 2024Est. completion: Sep 20263,000 patients
N/AActive Not Recruiting

Antibiotic Prophylaxis With Routine Ureteral Stent Removal

Start: Jan 2016Est. completion: Mar 2025
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space