Type 1 Diabetes
Pipeline by Development Stage
Drug Modality Breakdown
On Market (4)
Approved therapies currently available
Competitive Landscape
17 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 13,309 patients across 50 trials
Association of Type 1 Diabetes Mellitus in Offsprings With Positive Parental History of Diabetes
Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Elect to Fast During Ramadan
Beneficial Effect of Insulin Glulisine by Lipoatrophy and Type 1 Diabetes (LAS)
Optimal Insulin Correction Factor in Post- High Intensity Exercise Hyperglycemia in Adults With Type 1 Diabetes (FIT)
Sitagliptin and Glucagon Counterregulation
Efficacy of Sitagliptin and Glibenclamide on the Glucose Variability in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431-355)
Effects of Sitaglpitin on Endothelial Function During the OGTT in T2DM
TOFO Insulin Combination Trial
Sitagliptin and Brown Adipose Tissue
Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney Transplant
Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy
Basal-bolus and Premixed Insulin Regimens in Hospitalized Patients With Type 2 Diabetes (PININ Study)
52 Week Trial of Liraglutide in Type 1 Diabetes
Role of Mobile Technology to Improve Diabetes Care in Adults With Type 1 Diabetes: the REMOTE-T1D Study, a Pilot Study
A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)
Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus
Simplified Insulin Protocol Using Lantus in Elderly
Satisfaction of Treatment Among Elderly Patients With Insulin Therapy
Various Insulin Regimens for Diabetic Inpatients With Cirrhosis Trial
Performance Evaluation of Blood Glucose Monitoring Systems
Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia
Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)
Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)
Basal Bolus Versus Basal Insulin in Type 2 Diabetes Mellitus (T2DM)
Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency
Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism
The Effect of Sitagliptin in Type 2 Diabetes Mellitus With Inadequate Glycemic Control (MK0431-118)
Bone Turnover in Type 2 Diabetes Patients
ALPHA Sitagliptin Add on to Metformin (0431-103)
Effect of Insulin Glulisine Compared to Insulin Aspart and Insulin Lispro When Administered by Continuous Subcutaneous Insulin Infusion (CSII) on Specific Pump Parameters in Patient With Type 1 Diabetes Mellitus
Study of Safety and Effectiveness of Apidra® in Combination With Basal Insulin in Patients With Type 1 & 2 Diabetes Mellitus
Insulin Analogues and Severe Hypoglycaemia
A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes
Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy
Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)
A Study Evaluating the Efficacy and Safety of Adding Symlin® to Lantus® (Insulin Glargine) in Subjects With Type 2 Diabetes
Basal/Bolus Versus Sliding Scale Insulin In Hospitalized Patients With Type 2 Diabetes
Effect of Glargine Insulin on Glucose Control in Hospitalized Patients Who Receive Tube Feedings
Rosiglitazone and Insulin in T1DM Adolescents
Clinical Study for Dimethyl Fumarate in Preserving Islet β-Cell Function in Type 1 Diabetes Mellitus
An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in Combination With Oral Antidiabetic Drug(s)
A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)
Randomized Sitagliptin Withdrawal Study (MK-0431-845)
Double-blind Ipragliflozin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Sitagliptin (MK-0431J-843)
Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842)