Traumatic Brain Injury
Pipeline by Development Stage
On Market (1)
Approved therapies currently available
Competitive Landscape
38 companies ranked by most advanced pipeline stage
+8 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 6,283 patients across 50 trials
Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
Optimized Therapy in Severe Traumatic Brain Injured Patients
Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI)
NeuroAiD II™ (MLC901) in Mild Traumatic Brain Injury
Efficacy of VAS203 (Ronopterin) in Patients With Moderate and Severe Traumatic Brain Injury
Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury
The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT)
Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury and Cognitive Impairment
Sodium Lactate in Severe TBI
Insulin-sensitizing NE3107 in Improving Sleep and Fatigue in Subjects With Traumatic Brain Injury
Sleep Management And Recovery After Traumatic Brain Injury in Kids: Pilot Intervention of Melatonin
Exogenous Sodium Lactate Infusion in Traumatic Brain Injury (ELI-TBI)
IL-1ra Dose-range Study for Moderate-to-severe TBI Patients
A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)
Prehospital Tranexamic Acid Use for Traumatic Brain Injury
Copenhagen Head Injury Ciclosporin (CHIC) Study
Safety of Dexmedetomidine in Severe Traumatic Brain Injury
Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury
Safety and Tolerability of Oxycyte in Patients With Traumatic Brain Injury (TBI)
A Phase 2a Dose Escalation Study With SLV334 in Patients With Traumatic Brain Injury.
An Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of JNJ-17299425 in Participants With Traumatic Brain Injury
Study of Oxycyte in Severe Closed Head Injury
Feasibility Study of Duloxetine in the Treatment of Depression in Patients With Traumatic Brain Injury
Heart Rate Variability Biofeedback Following Traumatic Brain Injury
Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI)
Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury
Traumatic Brain Injury and Yoga
Augmentation of Cognitive Training in Children With TBI With D-Cyloserine
Traumatic Brain Injury Peripheral Nerve Study
Effects of TT301 on Cytokine Levels Post Endotoxin Challenge
Stem Cell Therapy in Traumatic Brain Injury
A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers
Modulating Inflammation in Neuro-Trauma
Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials
Non-invasive Deep Brain Stimulation to Improve Spatial Navigation Abilities in Individuals Following Traumatic Brain Injury
Evaluation of the Abbott i-STAT TBI Biomarker Test
Plasticity of Deep Brain Structures in Mild Cognitive Impairment and Healthy Aging
SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBI
Clinical Evaluation of the i-STAT TBI Test
Telephone Delivery of Cognitively Augmented Behavioral Activation (CABA)
Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury
Restorative Neuromodulation for Upper Extremity Functions
VR-based EF Rehabilitation for Pediatric TBI
Shared Decision Making to Improve Goals-of-Care Decisions for Families of Severe Acute Brain Injury Patients
Oculomotor Assessment of Traumatic Brain Injury (TBI)
Strength and Awareness in Action: an Intervention for Post-Acute TBI Headaches (SAA-TBI)
Epigenetic Effects on Traumatic Brain Injury Recovery
Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Brain Injury Assessment Study at Hennepin County Medical Center
Strategic Memory and Reasoning Training for Cognitive Problems
Phase Legend
Key Insights
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.